Results 61 to 70 of about 2,192 (198)
Physiological disturbances and histological damages of reproductive system in male rats resulted by metformin [PDF]
Caspian Journal of Environmental Sciences, 2022 The current study was designed to evaluate the effects of metformin in some physiological and histological parameters of reproductive system in the diabetic male rats experimentally. Forty rats were randomly divided into four groups. The (control) first
Fatima Aziz Mahdi Al-badry
doaj +1 more source
Current methods to analyze lysosome morphology, positioning, motility and function
Traffic, Volume 23, Issue 5, Page 238-269, May 2022., 2022 Lysosomes play essential roles beyond their well‐known degradative function, including nutrient sensing, intracellular signalling and metabolism. To better understand these functions, it is essential to employ the best methodological approaches and know their advantages and limitations.
Duarte C. Barral +32 more
wiley +1 more source
Evaluation of Protamine Deficiency and DNA Fragmentation in Two Globozoospermia Patients Undergoing ICSI [PDF]
International Journal of Fertility and Sterility, 2007 The aim of this report has been evaluating protamine content and DNA integrity of two patients with globozoospermia undergoing Intra Cytoplasmic Sperm Injection (ICSI).Semen analysis was carried out according to WHO criteria. Protamine deficiency and DNA
Mohammad Reza Deemeh +3 more
doaj +1 more source
Redox Biology, 2021 Fibrous sheath interacting protein 1 (Fsip1) is a cytoskeletal structural protein of the sperm flagellar proteome. A few studies have reported that it plays a vital role in the tumorigenesis and cancer progression. However, little is known about the role
Yaser Gamallat +14 more
doaj +1 more source
Dynamics of Sun5 localization during spermatogenesis in wild type and Dpy19l2 knock-out mice indicates that Sun5 is not involved in acrosome attachment to the nuclear envelope. [PDF]
PLoS ONE, 2015 The acrosome is an organelle that is central to sperm physiology and a defective acrosome biogenesis leads to globozoospermia, a severe male infertility. The identification of the actors involved in acrosome biogenesis is therefore particularly important
Sandra Yassine +6 more
doaj +1 more source
How exome sequencing improves the diagnostics and management of men with non-syndromic infertility. [PDF]
AndrologyAbstract Male infertility affects approximately 17% of all men and represents a complex disorder in which not only semen parameters such as sperm motility, morphology, and number of sperm are highly variable, but also testicular phenotypes range from normal spermatogenesis to complete absence of germ cells.
Stallmeyer B, Dicke AK, Tüttelmann F.
europepmc +2 more sources
International Journal for Research in Applied Sciences and Biotechnology, 2021 Objective(s): Sperm-mediated oocyte activation depends upon suitable expression and assembly of sperm-borne oocyte-activating factors (SOAFs) during spermiogenesis. Several factors have been considered as candidates for oocyte activation in recent years.
Dhuha. S. Namaa +2 more
semanticscholar +1 more source
Biology of Reproduction, 2020 Globozoospermia (sperm with an abnormally round head shape) and asthenozoospermia (defective sperm motility) are known causes of male infertility in human patients.
K. Nozawa +9 more
semanticscholar +1 more source
A newly discovered mutation in PICK1 in a human with globozoospermia [PDF]
Asian Journal of Andrology, 2010 Globozoospermia is a human infertility syndrome caused by spermatogenesis defects (OMIM 102530). Acrosome plays an important role at the site of sperm-zonapellucida binding during the fertilization process. Thus, malformation of the acrosome is the most prominent feature seen in globozoospermia.
Gang, Liu, Qiu-Wen, Shi, Guang-Xiu, Lu
openaire +2 more sources
Asian Journal of Andrology, 2023 Male infertility is a major reproductive disorder, which is clinically characterized by highly heterogeneous phenotypes of abnormal sperm count or quality.
Si-Yi Zhao +5 more
doaj +1 more source