Results 61 to 70 of about 2,311 (205)
Successful pregnancies and a live birth after intracytoplasmic sperm injection in globozoospermia
Journal of Human Reproductive Sciences, 2009 Globozoospermia is a severe form of teratozoospermia characterized by round-headed acrosomeless spermatozoa. Here we present two successful pregnancies and a live birth after intracytoplasmic sperm injection.
Manish R Banker +4 more
doaj +1 more source
Endoplasmic Reticulum-Localized Transmembrane Protein Dpy19L1 Is Required for Neurite Outgrowth. [PDF]
PLoS ONE, 2016 The endoplasmic reticulum (ER), including the nuclear envelope, is a continuous and intricate membrane-bound organelle responsible for various cellular functions. In neurons, the ER network is found in cell bodies, axons, and dendrites.
Keisuke Watanabe +3 more
doaj +1 more source
Mechanism of Acrosome Biogenesis in Mammals
Frontiers in Cell and Developmental Biology, 2019 During sexual reproduction, two haploid gametes fuse to form the zygote, and the acrosome is essential to this fusion process (fertilization) in animals.
Muhammad Babar Khawar +4 more
doaj +1 more source
piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis. [PDF]
, 2015 MIWI catalytic activity is required for spermatogenesis, indicating that piRNA-guided cleavage is critical for germ cell development. To identify meiotic piRNA targets, we augmented the mouse piRNA repertoire by introducing a human meiotic piRNA cluster.
Burgess, Ralph +7 more
core +2 more sources
Middle East Fertility Society JournalBackground Globozoospermia is a rare male infertility disorder characterized by the presence in the ejaculate of round-headed sperm cells lacking an acrosome, a crucial structure for fertilization.
Wiem Ayed +10 more
doaj +1 more source
Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive Targets
Frontiers in Cell and Developmental Biology, 2020 With the continued steep rise of the global human population, and the paucity of safe and practical contraceptive options available to men, the need for development of effective and reversible non-hormonal methods of male fertility control is widely ...
Katarzyna Kent +9 more
doaj +1 more source
The role of acroblast formation during Drosophila spermatogenesis [PDF]
, 2016 Protein recycling is important for maintaining homeostasis of the Golgi and its cisternae. The Vps54 (Scat) protein, a subunit of the GARP tethering complex, is a central factor in retrograde transport to the trans-Golgi.
Fari, Karolina +3 more
core +5 more sources
Sperm defects in primary ciliary dyskinesia and related causes of male infertility [PDF]
, 2020 The core axoneme structure of both the motile cilium and sperm tail has the same ultrastructural 9 + 2 microtubular arrangement. Thus, it can be expected that genetic defects in motile cilia also have an effect on sperm tail formation.
Loebinger, Michael R. +4 more
core +2 more sources
Acrosomal biogenesis in human globozoospermia: immunocytochemical, ultrastructural and proteomic studies [PDF]
Human Reproduction, 2012 Acrosome biogenesis is a key event in sperm differentiation that depends on the proper interaction between the Golgi complex and the nuclear envelope of early spermatids. We studied the development, structure and biochemical characteristics of human acrosomes in germ cells and spermatozoa from testicular biopsies and semen samples of fertile men and ...
Alvarez Sedó, Cristian +2 more
openaire +3 more sources
EP300‐interacting inhibitor of differentiation 3 is required for spermatogenesis in mice
Andrology, Volume 13, Issue 7, Page 1901-1912, October 2025.Abstract Background Mammalian spermatogenesis is a highly complex process of cell proliferation, meiosis, and differentiation. A series of genes are expressed in an orderly and precise manner to ensure spermatogenesis, with chromatin undergoing intricate changes throughout.
Ping Zhang +7 more
wiley +1 more source