Results 71 to 80 of about 2,192 (198)
Chromosome aneuploidy in the spermatozoa of two men with globozoospermia [PDF]
The objective of this study was to determine the aneuploidy level in spermatozoa in two men with globozoospermia. Sperm nuclei were analysed by fluorescence in-situ hybridization (FISH) in two infertile males with globozoospermia. Dual FISH for chromosomes 7 and 9, 13 and 21, and triple FISH for chromosomes X, Y, and 18 was performed.
F, Morel +8 more
openaire +2 more sources
From azoospermia to macrozoospermia, a phenotypic continuum due to mutations in the ZMYND15 gene
Thanks to tremendous advances in sequencing technologies and in particular to whole exome sequencing (WES), many genes have now been linked to severe sperm defects.
Zine-Eddine Kherraf +7 more
doaj +1 more source
Mechanism of Acrosome Biogenesis in Mammals
During sexual reproduction, two haploid gametes fuse to form the zygote, and the acrosome is essential to this fusion process (fertilization) in animals.
Muhammad Babar Khawar +4 more
doaj +1 more source
Endoplasmic Reticulum-Localized Transmembrane Protein Dpy19L1 Is Required for Neurite Outgrowth. [PDF]
The endoplasmic reticulum (ER), including the nuclear envelope, is a continuous and intricate membrane-bound organelle responsible for various cellular functions. In neurons, the ER network is found in cell bodies, axons, and dendrites.
Keisuke Watanabe +3 more
doaj +1 more source
Toward Development of the Male Pill: A Decade of Potential Non-hormonal Contraceptive Targets
With the continued steep rise of the global human population, and the paucity of safe and practical contraceptive options available to men, the need for development of effective and reversible non-hormonal methods of male fertility control is widely ...
Katarzyna Kent +9 more
doaj +1 more source
Assisted reproductive treatments with hyperbaric oxygen therapy in male infertility
Objective: This study aimed to analyze the results of hyperbaric oxygen therapy (HBOT) in addition to assisted reproductive technologies in male infertility cases. Material and methods: Medical records of male infertility patients who had HBOT sessions
Kübra Özgök Kangal, Yaşar Özgök
doaj +1 more source
This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li +22 more
wiley +1 more source
Klinefelter syndrome and Y-chromosomal microdeletion analyses were once the only two genetic tests offered to infertile men. Analyses of aurora kinase C (AURKC) and DPY19L2 are now recommended for patients presenting macrozoospermia and globozoospermia ...
Leyla Ounis +13 more
doaj +1 more source
Résumé Alors que la stratégie actuelle d'analyse de génétique moléculaire de l'infertilité masculine est basée sur une approche dite "gène candidat", le développement des technologies de séquençage de nouvelle génération, comme le séquençage complet de l'
Farah Ghieh +7 more
doaj +1 more source
EP300‐interacting inhibitor of differentiation 3 is required for spermatogenesis in mice
Abstract Background Mammalian spermatogenesis is a highly complex process of cell proliferation, meiosis, and differentiation. A series of genes are expressed in an orderly and precise manner to ensure spermatogenesis, with chromatin undergoing intricate changes throughout.
Ping Zhang +7 more
wiley +1 more source

