Results 71 to 80 of about 2,311 (205)
Asian Journal of Andrology, 2015 Klinefelter syndrome and Y-chromosomal microdeletion analyses were once the only two genetic tests offered to infertile men. Analyses of aurora kinase C (AURKC) and DPY19L2 are now recommended for patients presenting macrozoospermia and globozoospermia ...
Leyla Ounis +13 more
doaj +1 more source
Assisted reproductive treatments with hyperbaric oxygen therapy in male infertility
Urology Research and Practice, 2021 Objective: This study aimed to analyze the results of hyperbaric oxygen therapy (HBOT) in addition to assisted reproductive technologies in male infertility cases. Material and methods: Medical records of male infertility patients who had HBOT sessions
Kübra Özgök Kangal, Yaşar Özgök
doaj +1 more source
Searching for candidate genes for male infertility [PDF]
, 2003 Aim: We describe an approach to search for candidate genes for male infertility using the two human genome databases: the public University of California at Santa Cruz (UCSC) and private Celera databases which list known and predicted gene sequences and ...
Armes, JE +4 more
core
Rapid Visualisation of Microarray Copy Number Data for the Detection of Structural Variations Linked to a Disease Phenotype [PDF]
, 2012 Whilst the majority of inherited diseases have been found to be caused by single base substitutions, small insertions or deletions (
Ali, M +10 more
core +3 more sources
Novel ACTL7A variants in males lead to fertilization failure and male infertility
Andrology, Volume 13, Issue 5, Page 1117-1126, July 2025.Abstract Background Total fertilization failure occurs in 1%–3% of all intracytoplasmic sperm injection cycles. Genetic defects are found to be crucial causes responsible for total fertilization failure after intracytoplasmic sperm injection. However, the reported genes only elucidate a small proportion of total fertilization failure cases, and more ...
Meng Wang +6 more
wiley +1 more source
Basic and Clinical Andrology, 2021 Résumé Alors que la stratégie actuelle d'analyse de génétique moléculaire de l'infertilité masculine est basée sur une approche dite "gène candidat", le développement des technologies de séquençage de nouvelle génération, comme le séquençage complet de l'
Farah Ghieh +7 more
doaj +1 more source
Oocyte activation: The impact of calcium signals on fertilization [PDF]
, 2008 Fertilization is triggered by changes in intracellular calcium concentration. In mammals, these transients in ooplasmic calcium concentration take the form of repetitive spikes, so called calcium oscillations (Ca2+-oscillations).
De Sutter, Petra +2 more
core +1 more source
Fine characterisation of a recombination hotspot at the DPY19L2 locus and resolution of the paradoxical excess of duplications over deletions in the general population. [PDF]
PLoS Genetics, 2013 We demonstrated previously that 75% of infertile men with round, acrosomeless spermatozoa (globozoospermia) had a homozygous 200-Kb deletion removing the totality of DPY19L2.
Charles Coutton +9 more
doaj +1 more source
Teratozoospermia: spotlight on the main genetic actors in the human [PDF]
, 2017 BACKGROUND Male infertility affects >20 million men worldwide and represents a major health concern. Although multifactorial, male infertility has a strong genetic basis which has so far not been extensively studied.
Arnoult, Christophe +4 more
core
Molecular triggers of egg activation at fertilization in mammals [PDF]
, 2016 In mammals, the sperm activates the development of the egg by triggering a series of oscillations in the cytosolic-free Ca2+concentration (Ca2+i). The sperm triggers these cytosolic Ca2+ioscillations after sperm–egg membrane fusion, as well as after ...
Sanders, Jessica R., Swann, Karl
core +1 more source