Results 31 to 40 of about 3,983 (152)
Background Alpha-mangostin (AM) has been shown to have hypoglycemic activity. This study aimed to analyze the effects of AM at a dose of 100 mg/kg and 200 mg/kg to alleviate hyperuricemia and renal dysfunction on high-fat/high-glucose diet and low dose ...
Vivian Soetikno +3 more
doaj +1 more source
Hyperuricemia during Pregnancy Leads to a Preeclampsia-Like Phenotype in Mice
Hyperuricemia is a common feature in pregnancies compromised by pre-eclampsia, a pregnancy disease characterized by hypertension and proteinuria. The role of uric acid in the pathogenesis of pre-eclampsia remains largely unclear.
Benjamin P. Lüscher +3 more
doaj +1 more source
Background: Nuclear receptor binding protein 1 (NRBP1) and ATP-binding cassette subfamily G member 2 (ABCG2) was the gout risk gene and high-capacity urate exporter respectively.
Qiankun Zhang, Hang Fang, Zaihua Zhu
doaj +3 more sources
Objective: In order to explore the uric acid-lowering activity and mechanism of four traditional Chinese medicines, celery seed, dandelion, chicory and corn silk, and analysis of the main functional components with uric acid-lowering effect in these four
Lingtai JIN +3 more
doaj +1 more source
Lactobacillus acidophilus Fermented Dandelion Improves Hyperuricemia and Regulates Gut Microbiota
Foodborne prevention and treatment of hyperuricemia (HUA) has received widespread attention. Lactic acid bacteria (LAB) can improve intestinal function, while traditional medicine dandelion has the functions of detoxification and detumescence.
Qianwen Ma +9 more
doaj +1 more source
An edible sea cucumber Holothuria atra has been hypothesized to have medicinal benefits against hyperuricemia owing to its bioactive compounds, including mono- and poly-unsaturated fatty acids. Herein, we aimed to investigate the fatty acids-rich extract
Ikhsan Ikhsan +5 more
doaj +1 more source
Hyperuricemia plays a critical causative role in gout. In contrast, hyperuricemia has a protective effect in neurodegenerative disorders, including Alzheimer’s Disease.
Asim K. Mandal (7525190) +1 more
core +1 more source
Immunoreactivity of urate transporters, GLUT9 and URAT1, is located in epithelial cells of the choroid plexus of human brains [PDF]
香川大学Kagawa University博士(医学)Abstract It has been suggested that urate plays a protective role in neurons, while hyperuricemia is correlated with atherosclerosis and cardiovascular disease.
Uemura, Naoya +2 more
core +1 more source
Glucose transport across the chondrocyte membrane is essential for chondrogenesis and the development of the skeletal system. We have previously used RT-PCR to show that fully developed human articular chondrocytes express transcripts for the GLUT1 and ...
Mobasheri, A +6 more
core +2 more sources
This study aimed to examine the association between serum uric acid and incident type 2 diabetes mellitus. The study included 5719 subjects (2588 men) aged ≥ 30 years without T2DM at baseline. Multivariate Cox proportional hazard analyses were applied using SUA as continuous and categorical variables. Subjects followed up during a median follow‐up of 8.
Nahid Kord +5 more
wiley +1 more source

