Results 41 to 50 of about 3,983 (152)
PLACENTAL URIC ACID TRANSPORTER GLUT9 IS MODULATED BY FREE IODINE [PDF]
PLACENTAL URIC ACID TRANSPORTER GLUT9 IS MODULATED BY FREE IODINE Objectives: Materno-fetal transplacental transport is crucial for the fetal well-being.
Fine, Michael +7 more
core
The haplotype association among all 21 SNPs in the GLUT9 gene.
The haplotype association among all 21 SNPs in the GLUT9 gene.
Dongmei Meng (180462) +12 more
core +1 more source
Background: Saengmaeksan (SMS) is a traditional Korean medicine composed of three herbs, Panax ginseng, Schisandra chinensis, and Liriope platyphylla. SMS is used to treat respiratory and cardiovascular disorders.
Yoon-Young Sung +2 more
doaj +1 more source
Farnesoid X receptor prevents hyperuricemia via activating ATP‐binding cassette subfamily G member 2
Farnesoid X receptor (FXR) activation reduces serum uric acid levels by upregulating the intestinal urate transporter ATP‐binding cassette subfamily G member 2 (ABCG2). These findings uncover a novel metabolic pathway for urate excretion and suggest that FXR agonists (e.g., obeticholic acid), represent a promising therapeutic strategy for the treatment
Rui Li +5 more
wiley +1 more source
ABSTRACT Aim Sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are known to reduce serum urate levels, yet their specific impact on gout incidence in the Korean population remains underexplored. We investigated the association between SGLT2i use and incident gout using real‐world data and Mendelian randomisation (MR) analysis. Materials and Methods We
Hong Sang Choi +7 more
wiley +1 more source
Objective: Hyperuricemia is an excess of urate in blood. The kidneys play important parts in urate excretion, which involves handling reabsorption and secretion.
Yu Wang +4 more
doaj +1 more source
In 5773 adults followed for ~5 years, higher EAT–Lancet diet adherence was consistently associated with lower incident hyperuricemia and lower serum uric acid. Associations were observed across three EAT–Lancet scoring approaches and persisted after adjustment for established dietary‐quality indices. Baseline HOMA‐IR may partly mediate this association,
Farzam Kamrani +7 more
wiley +1 more source
Association Between TyG‐WC and Gout in American Adults: A Cross‐Sectional Study of NHANES 2003–2018
ABSTRACT Background and Aims The triglyceride‐glucose (TyG) index is widely used as a surrogate marker of insulin resistance. Indices that combine TyG with anthropometric measures may better reflect metabolic dysfunction and central adiposity. However, evidence regarding the association between TyG‐waist circumference (TyG‐WC) and gout among U.S ...
Shenlong Yi +7 more
wiley +1 more source
Uric acid is the end product of purine metabolism. Uric acid transporters in the renal proximal tubule plays a key role in uric acid transport. Functional abnormalities in these transporters could lead to high or low levels of uric acid in the blood ...
Shahsavari, S +5 more
core +1 more source
Glucose Transporter 1 in Health and Disease
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source

