Results 41 to 50 of about 401 (96)
Investigation of the role of the glucose-6-phosphate translocase in the activation of autophagy and glycogen-selective autophagy in glycogen storage disease type IB patients [PDF]
, 2023 Introduction: Glycogen storage disease type Ib (GSD-Ib) is characterized by a deficiency of glucose-6- phosphate translocase (G6PT) encoded by the SLC37A4 gene, affecting glucose homeostasis and disrupting autophagy.
Jocić, Nikola +11 more
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Immune modulation through secretory autophagy
Journal of Cellular Biochemistry, Volume 125, Issue 11, November 2024.Abstract Autophagy is a central mechanism of cellular homeostasis through the degradation of a wide range of cellular constituents. However, recent evidence suggests that autophagy actively provides information to neighboring cells via a process called secretory autophagy. Secretory autophagy couples the autophagy machinery to the secretion of cellular
Andreas Weigert, Lina Herhaus
wiley +1 more source
The FASEB Journal, Volume 38, Issue 19, 15 October 2024.Natural products can influence various intracellular stress responses, thereby controlling the malignant biological behavior of ovarian cancer and affecting its progression. Abstract Autophagy is a conservative catabolic process that typically serves a cell‐protective function.
Dongxiao Li, Danbo Geng, Min Wang
wiley +1 more source
The glycogenolytic enzyme acid α‐glucosidase is expressed in the bovine uterine endometrium
Reproduction in Domestic Animals, Volume 59, Issue 6, June 2024.Abstract Progesterone has been shown to stimulate glycogen catabolism in uterine epithelial cells. Acid α‐glucosidase (GAA) is an enzyme that breaks down glycogen within lysosomes. We hypothesized that progesterone may stimulate glycogenolysis in the uterine epithelium via GAA.
Malia D. Berg, Matthew Dean
wiley +1 more source
Uncovering the Role of Glycogen in Brown Adipose Tissue
, 2021 International audienceThe presence of glycogen in the brown adipose tissue (BAT) has been described 60 years ago. However, the role of this energetic storage in brown adipocytes has been long time underestimated.
Mayeuf-Louchart, Alicia
core +1 more source
THE ROLE OF GLYCOGEN ACCUMULATION AND UTILIZATION IN METASTTIC BREAST CANCER PROGRESSION
, 2022 Breast cancer is a significant public health concern being the second leading cause of cancer-related death in women, with a projected 43,250 deaths in the US in 2022.
Emily Michele Hicks (14221748)
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Autophagy at the crossroads of catabolism and anabolism [PDF]
, 2015 Autophagy is a conserved catabolic process that degrades cytoplasmic constituents and organelles in the lysosome. Starvation-induced protein degradation is a salient feature of autophagy but recent progress has illuminated how autophagy, during both ...
Kaur, Jasvinder, Debnath, Jayanta
core +1 more source
The ER - Glycogen Particle - Phagophore Triangle: A Hub Connecting Glycogenolysis and Glycophagy? [PDF]
, 2019 Glycogen particle is an intracellular organelle, which serves as a carbohydrate reserve in various cells. The function of glycogen is not entirely known in several cell types.
Bánhegyi, Gábor, Mandl, József
core +1 more source
Molecular MetabolismObjective: Carbohydrate Response Element Binding Protein (ChREBP) is a glucose 6-phosphate (G6P)-sensitive transcription factor that acts as a metabolic switch to maintain intracellular glucose and phosphate homeostasis.
K.A. Krishnamurthy +13 more
doaj +1 more source
Molecular mechanisms of the cardiac glycogen response to physiological metabolic stress
, 2021 Full Text is available to authenticated members of The University of Auckland only.Background: The heart relies mainly on the oxidation of fatty acids and glucose for energy production, stored in the heart as triglycerides and glycogen respectively ...
James, Samuel
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