Results 91 to 100 of about 25,840 (267)

Lannea coromandelica (Houtt.) Merr.: A Comprehensive Review of Its Ethnomedicinal Uses, Phytochemistry and Pharmacological Activity

Health Science Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background and Aims Lannea coromandelica (Houtt.) Merr., a deciduous tropical tree of the Anacardiaceae family, is traditionally used in Asian ethnomedicine to treat diabetes, skin diseases, ulcers, inflammation, and microbial infections. This review aims to consolidate current knowledge on its ethnomedicinal applications, phytochemistry ...
Nawfal Hasan Siam, Sumaya Akter, Anika Rahman, Taniza Tasnim, Md. Mhamudul Huda Ruhed, Anika Ahmed, Naznin Rahman, Afsana Akter Mim, Tasnim Tabassum, Md. Mazharul Islam Chowdhury, Jakir Ahmed Chowdhury   +10 more
wiley   +1 more source

Biosynthesis and metabolic degradation of sphingolipids not containing sialic acid

Journal of Lipid Research, 1972
Interest in sphingolipid metabolism has increased rapidly during the past decade, and many of the steps involved in the biosynthesis and metabolic degradation of sphingolipids are now known. In this review these studies are critically exmined.
Pierre Morell, Peter Braun
doaj   +1 more source

Structural Complexity of Non-acid Glycosphingolipids in Human Embryonic Stem Cells Grown under Feeder-free Conditions*

Journal of Biological Chemistry, 2013
Background: Carbohydrate epitopes are often used as markers for characterization of human embryonic stem cells (hESC). Results: Several glycosphingolipids not previously found in hESC were characterized.
Angela Barone, John Benktander, J. Ångström, A. Aspegren, P. Björquist, S. Teneberg, M. Breimer   +6 more
semanticscholar   +1 more source

Therapeutic Effects of Nizubaglustat in a Mouse Model of GM2 Gangliosidosis

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Nizubaglustat is a novel selective inhibitor of glucosylceramide synthase (GCS) and the non‐lysosomal glucocerebrosidase (NLGase, GbA2) with brain penetrant properties. It is currently in clinical development as an oral treatment for rare lysosomal storage diseases with neurological involvement. One such disease group called GM2 gangliosidosis,
Kyle Landskroner, Kshitiz Singh, Melissa Mitchell, Jagdeep S. Walia   +3 more
wiley   +1 more source

Structure and biological functions of fungal cerebrosides

Anais da Academia Brasileira de Ciências, 2004
Ceramide monohexosides (CMHs, cerebrosides) are glycosphingolipids composed of a hydrophobic ceramide linked to one sugar unit. In fungal cells, CMHs are very conserved molecules consisting of a ceramide moiety containing 9-methyl-4,8-sphingadienine in ...
Barreto-Bergter Eliana, Pinto Marcia R., Rodrigues Marcio L.   +2 more
doaj  

CDG due to Defective Membrane Transporters: Update

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Congenital disorders of glycosylation are genetic defects in the glycoprotein and glycolipid glycan assembly and attachment. Some 200 CDG have been reported since the first clinical description in 1980. Most CDG are enzymatic deficiencies, but 13 (6.5%) are defects in the ER, Golgi apparatus (GA), and plasma membrane transporters.
D. Quelhas, C. R. Ferreira, J. Jaeken
wiley   +1 more source

Structural analysis of blood-group ABH, I, i, Lewis and related glycosphingolipids. Application of FAB mass spectrometry and high resolution proton NMR [PDF]

, 1984
Heinz Egge, J. Da̧browski, Peter Hanfland   +2 more
openalex   +1 more source

From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1

Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT GM1 gangliosidosis is a rare, progressively neurodegenerative lysosomal storage disorder characterized by profound central nervous system involvement and substantial clinical heterogeneity. The development of reliable biomarkers is essential for tracking disease progression, stratifying patients, and advancing clinical trial readiness. Primary
Krista Casazza, Roberto Giugliani, Debra S. Regier, Jeanine Jarnes   +3 more
wiley   +1 more source

The Glycosphingolipid, Lactosylceramide, Regulates β1-Integrin Clustering and Endocytosis [PDF]

, 2005
Deepak Sharma, Jennifer C. Brown, Zhi-jie Jey Cheng, Eileen L. Holicky, David L. Marks, Richard E. Pagano   +5 more
openalex   +1 more source

Supplementary table S1 from Efficacy and Safety of Glycosphingolipid SSEA-4 Targeting CAR-T Cells in an Ovarian Carcinoma Model

, 2023
Héctor J. Monzó, Kerttu Kalander, Marko Hyytiäinen, Endrit Elbasani, Johanna Wall, Lidia Moyano‐Galceran, Jayendrakishore Tanjore Ramanathan, Joonas Jukonen, Pirjo Laakkonen, Ari Ristimäki, Joseph W. Carlson, Kaisa Lehti, Sahar Salehi, Pauli Puolakkainen, Caj Haglund, Hanna Seppänen, Sirpa Leppä, Päivi M. Ojala   +17 more
openalex   +1 more source