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Intracellular organelles carry out many of their functions by engaging in extensive interorganellar communication through specialized membrane contact sites (MCSs) formed where two organelles tether to each other or to the plasma membrane (PM) without ...
Jason Andrew Weesner +3 more
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Role of Globotriaosylceramide in Physiology and Pathology
At first glance, the biological function of globoside (Gb) clusters appears to be that of glycosphingolipid (GSL) receptors for bacterial toxins that mediate host-pathogen interaction.
Ana Beatriz Celi +6 more
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Glycosphingolipid Functions [PDF]
The combination of carbohydrate and lipid generates unusual molecules in which the two distinctive halves of the glycoconjugate influence the function of each other. Membrane glycolipids can act as primary receptors for carbohydrate binding proteins to mediate transmembrane signaling despite restriction to the outer bilayer leaflet.
openaire +3 more sources
Micellar properties of glycosphingolipids in aqueous media.
The aggregation properties of neutral glycosphingolipids and gangliosides were investigated by ultracentrifugal sedimentation and gel permeation chromatography. Initially, glycosphingolipids in buffer formed high molecular aggregates.
B Ulrich-Bott, H Wiegandt
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Glycosphingolipids: synthesis and functions [PDF]
Glycosphingolipids (GSLs) comprise a heterogeneous group of membrane lipids formed by a ceramide backbone covalently linked to a glycan moiety. Hundreds of different glycans can be linked to tens of different ceramide molecules, giving rise to an astonishing variety of structurally different compounds, each of which has the potential for a specific ...
G. D’Angelo +3 more
semanticscholar +3 more sources
The Role of Glycosphingolipids in Immune Cell Functions
Glycosphingolipids (GSLs) exhibit a variety of functions in cellular differentiation and interaction. Also, they are known to play a role as receptors in pathogen invasion. A less well-explored feature is the role of GSLs in immune cell function which is
Tao Zhang +3 more
semanticscholar +1 more source
Biochemical studies on sphingolipids of Artemia franciscana: novel neutral glycosphingolipids[S]
Neutral glycosphingolipids containing one to six sugars in their oligosaccharide chains have been isolated from cysts of the brine shrimp Artemia franciscana.
Hisao Kojima +5 more
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Enterotoxigenic F4-fimbriated Escherichia coli is associated with diarrheal disease in neonatal and postweaning pigs. The F4 fimbriae mediate attachment of the bacteria to the pig intestinal epithelium, enabling an efficient delivery of diarrhea-inducing
Annelies Coddens +6 more
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Determination of long-chain base in glycosphingolipids with fluorescamine
A method is described for determining the longchain base content of glycosphingolipids after acid hydrolysis, using the new reagent fluorescamine. The reaction is sensitive and can be used to characterize or measure glycosphingolipids in quantities ...
Alemka Kisic, Maurice M. Rapport
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Phospholipase A2 activity against mixed monolayers of dilauroylphosphatidic acid or dilauroylphosphatidylcholine with glycosphingolipids can be reversibly modulated by external constant electrostatic fields.
Bruno Maggio
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