Results 111 to 120 of about 52,375 (251)

Vergleich dreier Ringversuche zur radioimmunologischen Thyrotropin-Bestimmung nach dem "Münchner Modell" [PDF]

, 1983
Peer ...
Habermann, J., König, A., Marschner, I., Scriba, Peter Christian, van Thiel, D., Wood, W. G.   +5 more
core   +2 more sources

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation [PDF]

, 1998
A transient COS-7 cell expression system was used to investigate the functional domain arrangement of tissue inhibitor of metalloproteinases-3 (TIMP-3), specifically to assess the contribution of the amino- and carboxylterminal domains of the ...
Barker, M.D., Langton, K.P., McKie, N.
core  

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, EarlyView.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source

Structural Basis for Trivalent Cross‐Linking of a Patient‐Derived IgE Antibody by the Major Peanut Allergen Ara h 2.0201

Allergy, EarlyView.
Graphical The crystal structure of a major peanut allergen Ara h 2.0201 in a complex with a human‐derived IgE Fab fragment has been determined. The immunocomplex shows the trivalent binding of Fabs, creating a cross‐linked structure effective in the formation of large complexes on the surface of effector cells. Hydroxylation of proline has implications
Tarja Parkkinen, Heidi Heiniluoto, Janne Jänis, Kristiina Takkinen, Juha Rouvinen   +4 more
wiley   +1 more source

Risk factors of atherosclerosis in patients with history of breast cancer

Pteridines, 2013
The aim of the present study was to evaluate the prevalence of the risk factor of atherosclerosis in patients with history of breast cancer. C-reactive protein, lipoprotein (a), cholesterol, high-density lipoprotein (HDL) cholesterol, low-density ...
Šrámek Vlastislav, Melichar Bohuslav, Indráková Jarmila, Študentová Hana, Kalábová Hana, Vrána David, Lukešová Lucie, Adam Tomáš, Hlídková Eva, Juráňová Jarmila, Petrová Pavla, Krčmová Lenka Kujovská, Solichová Dagmar   +12 more
doaj   +1 more source

Hepatocyte TrkB Acts as a Gatekeeper Against MASH‐Related Liver Fibrosis by Suppressing the TGFβ/CCL2 Axis and Macrophage Infiltration

Cell Proliferation, EarlyView.
Hepatocyte TrkB is identified as a critical gatekeeper against MASH‐related fibrosis. Mechanistically, TrkB inhibits the TGFβ/SMAD3/FOS axis to suppress CCL2 secretion, thereby blocking pathogenic macrophage recruitment and ameliorating liver fibrosis.
Yueying Chen, Jiayi Wei, Shuxuan Li, Kefan Yin, Heming Wang, Yicheng Zhao, Shuqiang Weng, Xizhong Shen, Guangqi Song, Changfeng Zhu, Qunyan Yao, Ling Dong   +11 more
wiley   +1 more source

Expression and clinical significance of Sonic hedgehog in renal interstitial fibrosis of patients with diabetic kidney disease

Linchuang shenzangbing zazhi, 2017
Objective To investigate the expression of Sonic hedgehog(Shh)in diabetic kidney disease(DKD)and its correlation to renal interstitial fibrosis.Methods Forty patients with DKD were enrolled and 12 confirmed normal renal tissues adjacent to the renal ...
HOU Shi-hui, LI Yi, GUAN Tao, LIU Jun-hui, ZHAO Jing-hong, HUANG Yunjian   +5 more
doaj  

Cystatin C as a predictor of renal recovery and in hospital mortality in patients with acute kidney injury and liver cirrhosis

BMC Nephrology
Background Acute kidney injury (AKI) is a common and serious complication in patients with liver cirrhosis, with pre-renal AKI and acute tubular necrosis being the most frequent underlying causes.
Eman Nagy, Ahmed H. Abdelfattah, Nagy Sayed-Ahmed, Sadiq Ahmed   +3 more
doaj   +1 more source

Identification of cryptic nuclear localization signals in the prion protein

Neurobiology of Disease, 2003
Abnormal transport of C-terminally truncated prion protein (PrP) to the nucleus has been reported in cell models of familial prion disorders associated with a stop codon mutation at residues 145 or 160 of the PrP.
Yaping Gu, Joerg Hinnerwisch, Rebecca Fredricks, Sudheera Kalepu, Ravi Shankar Mishra, Neena Singh   +5 more
doaj   +1 more source