Results 71 to 80 of about 26,147 (300)

Progress on Synthetic Biology for Steviol Glycosides Biosynthesis

Shipin gongye ke-ji
Stevioside, also known as stevia, is a class of diterpenoids extracted from stevia with high sweetness, low calories, safety and non-toxicity, hypoglycemic, hypotensive, and other physiological characteristics.
Mengyu LIU, Hailin HE, Ting MA, Xiaochun SU, Yifei DING, Jinxuan WANG, Yinfeng LEI, Shubo LI   +7 more
doaj   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

Animal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen, Nana Jing, Shiyu Tao, Mingyue Fei, Wentao Lv, Hua Yang, Yingping Xiao, Haiqin Wu   +7 more
wiley   +1 more source

Engineering a Function into a Glycosyltransferase

Chemistry & Biology, 2009
As glycosyltransferases found in nature often show distinct substrate specificity, glycosyltransferase engineering is an important research field. In this work, we were able to introduce an activity into a glycosyltransferase involved in natural product (landomycin E) biosynthesis.
Krauth, Christine, Fedoryshyn, Marta, Schleberger, Christian, Luzhetskyy, Andriy, Bechthold, Andreas   +4 more
openaire   +3 more sources

Disulfide Bond–Modified Proteomics Reveals the Effects of Riboflavin on Protein Folding Dynamics

Animal Research and One Health, EarlyView.
Riboflavin deficiency impairs oxidative protein folding, causing ER misfolded protein accumulation, CHOP activation, and apoptosis, revealing a role of riboflavin in proteostasis. ABSTRACT Riboflavin is a crucial micronutrient essential for maintaining cellular homeostasis, acting as an important precursor for flavoproteins that utilize flavin ...
Bo Zhang, Shuisheng Hou, Jing Tang
wiley   +1 more source

Deciphering glycosylation-driven prognostic insights and therapeutic prospects in glioblastoma through a comprehensive regulatory model

Frontiers in Oncology
The oncogenesis and development of glioblastoma multiforme have been linked to glycosylation modifications, which are common post-translational protein modifications.
Xingyi Jin, Zhuo Chen, Hang Zhao
doaj   +1 more source

High Expression of the Sd^a Synthase B4GALNT2 Associates with Good Prognosis and Attenuates Stemness in Colon Cancer

Cells, 2020
Background: The carbohydrate antigen Sda and its biosynthetic enzyme B4GALNT2 are highly expressed in normal colonic mucosa but are down-regulated to a variable degree in colon cancer tissues.
Michela Pucci, Inês Gomes Ferreira, Martina Orlandani, Nadia Malagolini, Manuela Ferracin, Fabio Dall’Olio   +5 more
doaj   +1 more source

The yeast expression system for recombinant glycosyltransferases [PDF]

, 2018
Glycosyltransferases are increasingly being used for in vitro synthesis of oligosaccharides. Since these enzymes are difficult to purify from natural sources, expression systems for soluble forms of the recombinant enzymes have been developed.
Malissard, Martine, Zeng, Steffen, Berger, Eric   +2 more
core  

Seasonal drivers of plant–soil–microbial community structure and functions in Western Himalayan grasslands, Pakistan

Grassland Research, EarlyView.
Plant species richness was greater in summer in both alpine and subalpine grassland ecosystems. Soil moisture demonstrates significant positive correlations with soil organic carbon and total nitrogen across seasonal periods. Microbial α‐diversity peaks during summer but maintains functional stability across seasons.
Huma Ali, Muhammad Rafiq, Allan Degen, Ben Sparrow, Zhanhuan Shang   +4 more
wiley   +1 more source

Ganglioside biosynthesis. Characterization of uridine diphosphate galactose: GM2 galactosyltransferase in Golgiapparatus from rat liver

Journal of Lipid Research, 1976
An enzyme that transfers galactose from UDP-Gal to ganglioside GM2 (Tay-Sachs ganglioside) was concentrated 50 times in Golgi apparatus from rat liver relative to total homogenates.
F E Wilkinson, D J Morré, T W Keenan
doaj   +1 more source

Localization of Golgi-resident glycosyltransferases

, 2010
For many glycosyltransferases, the information that instructs Golgi localization is located within a relatively short sequence of amino acids in the N-termini of these proteins comprising: the cytoplasmic tail, the transmembrane spanning region, and the ...
Tu, Linna, Banfield, David Karl
core   +1 more source