Results 101 to 110 of about 6,124,437 (230)
Frontiers in PharmacologyPostoperative cognitive dysfunction (POCD) is a common and significant neurological complication, occurring more frequently in elderly individuals and those with frailty or underlying neurodegenerative conditions, though it is not limited to these ...
Sha-Sha Zhang +4 more
doaj +1 more source
Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk
Journal of Sleep Research, EarlyView.ABSTRACT This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study ‘Good Aging in Skåne’ (Mage = 68.4) with normal baseline sleep duration (6–8 h) were followed up to 20 years (Myears = 8.39). Self‐reported change was defined
Marieclaire Overton +2 more
wiley +1 more source
Frontiers in MicrobiologyBackgroundPainful diabetic neuropathy (PDN) is a common complication of type 2 diabetes, characterized by neuropathic pain and inflammation. Its pathogenesis involves oxidative stress, inflammatory responses, and dysfunction of the spinal cord glymphatic
Shuai-ying Jia +6 more
doaj +1 more source
Dynamic changes in glymphatic function in reversible cerebral vasoconstriction syndrome
The Journal of Headache and PainAbstract Background The pathophysiology of the reversible cerebral vasoconstriction syndrome (RCVS) remains enigmatic and the role of glymphatics in RCVS pathophysiology has not been evaluated. We aimed to investigate RCVS glymphatic dynamics and its clinical correlates.
Chia-Hung Wu +8 more
openaire +3 more sources
Journal of Sleep Research, EarlyView.ABSTRACT Cerebral small vessel disease (CSVD), a disorder that affects the cerebral microvasculature, is commonly associated with aging and may contribute to dementia and stroke. Increasing evidence suggests a link between CSVD and sleep disturbances, but the association remains poorly understood.
Mareike Ludwig +11 more
wiley +1 more source
, 2019 Glymphatic system is newly discovered pseudolymphatic system in brain and it plays an important role in the removal of interstitial metabolic waste products.
Jiang, Quan
core +1 more source
Periodontology 2000, EarlyView.Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata +3 more
wiley +1 more source
Contributions of vascular ageing to late‐onset Alzheimer's disease
Experimental Physiology, EarlyView.Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson +2 more
wiley +1 more source
Background: The association between whole-brain cerebral perfusion and glymphatic function has not been fully elucidated in Alzheimer’s disease (AD).
Xiuqin Jia +10 more
core +1 more source
Voluntary running enhances glymphatic influx in awake behaving, young mice
, 2018 Vascular pathology and protein accumulation contribute to cognitive decline, whereas exercise can slow vascular degeneration and improve cognitive function.
von Holstein-Rathlou, Stephanie +5 more
core +1 more source