Results 21 to 30 of about 1,450 (167)
Oncogenic Roles of GOLPH3 in the Physiopathology of Cancer [PDF]
International Journal of Molecular Sciences, 2020 Golgi phosphoprotein 3 (GOLPH3), a Phosphatidylinositol 4-Phosphate [PI(4)P] effector at the Golgi, is required for Golgi ribbon structure maintenance, vesicle trafficking and Golgi glycosylation.
Stefano Sechi +4 more
semanticscholar +5 more sources
Sequential Targeting Chondroitin Sulfate-Bilirubin Nanomedicine Attenuates Osteoarthritis via Reprogramming Lipid Metabolism in M1 Macrophages. [PDF]
Adv Sci (Weinh)M1 macrophages are excessively infiltrated and activated in the development of osteoarthritis. Here, a self‐assembled nanocarrier (designated as CSBN) based on chondroitin sulfate (CS)‐bilirubin (BR) conjugate is developed to reprogram lipid metabolism in macrophage activation by targeting the Golgi apparatus.
Deng C +10 more
europepmc +2 more sources
Mechanisms of GOLPH3 associated with the progression of gastric cancer: a preliminary study. [PDF]
PLoS ONE, 2014 STUDY DESIGN: To investigate the specific mechanisms by which Golgi phosphoprotein 3 (GOLPH3) affects the progression of gastric cancer and to explore its clinical significance.
Jinzhen Peng +7 more
doaj +4 more sources
Ecotoxicology and Environmental Safety, 2022 Nickel (Ni) compounds is recognized industrial carcinogen, which could increase the risk of lung cancer in Ni refineries workers. However, the underlying carcinogenic mechanism still remains to elucidate.
Tong Zhang +9 more
doaj +2 more sources
Ythdc1-p300-Klf5 Complex-Mediated Golgi Dysfunction Promotes Aortic Aneurysm. [PDF]
Adv Sci (Weinh)In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wang WL +22 more
europepmc +2 more sources
Identification of the client-binding site on the Golgi membrane protein adaptor Vps74/yGOLPH3 [PDF]
iScienceSummary: Vps74 and its mammalian counterpart GOLPH3 are COPI associated protein sorting adaptors that function to maintain the cisternal distributions of a diversity of Golgi integral membrane protein clients by binding to their short cytoplasmically ...
Agnieszka M. Lesniak +2 more
doaj +2 more sources
Proteomics Insights Into Lysosome Biogenesis and Maturation. [PDF]
ProteomicsABSTRACT Lysosomes constitute the main degradative organelle of most eukaryotic cells and are capable of breaking down a wide spectrum of biomolecules, including proteins, lipids, glycans, and DNA/RNA. They play crucial roles in the regulation of cellular homeostasis, acting as metabolic signaling centers for the correlation of nutrient availability ...
Hirn K, Fajardo-Callejón S, Winter D.
europepmc +2 more sources
Effect of GOLPH3 on cumulus granulosa cell apoptosis and ICSI pregnancy outcomes [PDF]
Scientific Reports, 2017 Previous studies have shown that GOLPH3 mediates cell growth, proliferation and differentiation and inhibits cell apoptosis; however, the role of GOLPH3 in cumulus granulosa cells and the value of GOLPH3 in predicting ICSI pregnancy outcomes remain ...
Dianliang Lin +7 more
doaj +3 more sources
Ecotoxicology and Environmental Safety, 2022 Nickel compounds, an international carcinogen in the industrial environment, increased the risk of lung inflammation even lung cancer in Ni refinery workers.
Tong Zhang +9 more
doaj +2 more sources
GOLPH3‐STIP1 Complex Activates STAT3 Through Exosome Secretion to Induce Colon Cancer Metastasis
Biotechnology JournalWith a high mortality rate, colon cancer (CC) is the third most common malignant tumor worldwide. The primary causes are thought to be the high invasiveness and migration of CC cells.
Yan‐ping Guo +5 more
semanticscholar +3 more sources