Results 41 to 50 of about 1,218 (144)
Cancer Cell International, 2022 Background Golgi phosphoprotein 3 (GOLPH3) has been frequently reported as an oncoprotein in a variety of tumors. However, its role in the cancer-associated intercellular signaling communication has not yet been explored.
Ying Gao +6 more
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BMC Cancer, 2018 Background Hepatocellular carcinoma (HCC) is the sixth most common cancer and the second leading cause of cancer-related deaths worldwide. Despite new technologies in diagnosis and treatment, the incidence and mortality of HCC continue rising.
Hongying Liu +9 more
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Reactive Oxygen Species: From Tumorigenesis to Therapeutic Strategies in Cancer
Cancer Medicine, Volume 14, Issue 10, May 2025.ABSTRACT Background Reactive oxygen species (ROS), a class of highly reactive molecules, are closely linked to the pathogenesis of various cancers. While ROS primarily originate from normal cellular processes, external stimuli can also contribute to their production. Cancer cells typically exhibit elevated ROS levels due to disrupted redox homeostasis,
Iqra Attique +6 more
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Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
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European Journal of Histochemistry, 2020 The incidence and mortality of gastric cancer have been increasing in recent years. MiR-126 and target genes have been studied in gastric cancer, but their studies with Golgi phosphoprotein 3 (GOLPH3) and related pathways in gastric cancer are rarely ...
Jiancai Ouyang +4 more
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Identification of a Novel Substrate for eEF2K and the AURKA‐SOX8 as the Related Pathway in TNBC
Advanced Science, Volume 12, Issue 14, April 10, 2025.This study reports that eukaryotic elongation factor 2 kinase (eEF2K) is a key regulator in promoting the progression of triple‐negative breast cancer (TNBC). Mechanistically, the authors identified AURKA as a novel substrate for eEF2K. In addition, the authors developed a new small molecule compound C4, which acts as a molecular glue for eEF2K and can
Xiaoya Wan +15 more
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Exploring Punicalagin Potential Against Cancers: A Comprehensive Review
Food Science &Nutrition, Volume 13, Issue 3, March 2025.This paper focuses on highlighting the therapeutic potential of punicalagin against tumors and cancers. Punicalagin inhibits tumor growth within the body through various cellular pathway interactions. This compound has efficacy in eliminating tumor cells from the liver, stomach, prostate, and lungs.
Muhammad Hammad Ul Hassan +12 more
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Effect of GOLPH3 on cumulus granulosa cell apoptosis and ICSI pregnancy outcomes
Scientific Reports, 2017 Previous studies have shown that GOLPH3 mediates cell growth, proliferation and differentiation and inhibits cell apoptosis; however, the role of GOLPH3 in cumulus granulosa cells and the value of GOLPH3 in predicting ICSI pregnancy outcomes remain ...
Dianliang Lin +7 more
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GOLPH3 protein controls organ growth by interacting with TOR signaling proteins in Drosophila
Cell Death and Disease, 2022 The oncoprotein GOLPH3 (Golgi phosphoprotein 3) is an evolutionarily conserved phosphatidylinositol 4-phosphate effector, mainly localized to the Golgi apparatus, where it supports organelle architecture and vesicular trafficking. Overexpression of human
Anna Frappaolo +6 more
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Frontiers in Oncology, 2022 The incidence and mortality of Prostate Cancer (PCa) worldwide correlate with age and bad dietary habits. Previously, we investigated the mRNA/miRNA role on PCa development and progression using high fat diet (HFD) fed mice.
Rocío Belén Duca +7 more
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