Results 61 to 70 of about 372,166 (319)

A new view of axon growth and guidance grounded in the stochastic dynamics of actin networks

open access: yesOpen Biology, 2023
The mechanism of axon growth and guidance is a core, unsolved problem in neuroscience and cell biology. For nearly three decades, our view of this process has largely been based on deterministic models of motility derived from studies of neurons cultured
Rameen Forghani   +3 more
doaj   +1 more source

Myosin II Activity Facilitates Microtubule Bundling in the Neuronal Growth Cone Neck [PDF]

open access: yes, 2008
SummaryThe cell biological processes underlying axon growth and guidance are still not well understood. An outstanding question is how a new segment of the axon shaft is formed in the wake of neuronal growth cone advance.
Burnette, Dylan T.   +5 more
core   +1 more source

Division of labor in the growth cone by DSCR1 [PDF]

open access: yesJournal of Cell Biology, 2016
Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 ...
Timothy M. Gomez, Timothy S. Catlett
openaire   +3 more sources

Radiotherapy medical physics in the Philippines: A contemporary overview

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose With cancer ranking as the third leading cause of death in the Philippines and a disparity in healthcare resources across regions, this research aimed to assess the state of radiotherapy medical physics in the country. Methodology The study utilized a comprehensive online survey with 94 structured questions answered by 19 clinics ...
John Paul C. Cabahug   +4 more
wiley   +1 more source

Posttranslational protein S-palmitoylation and the compartmentalization of signaling molecules in neurons

open access: yesBiological Research, 2002
Protein domains play a fundamental role in the spatial and temporal organization of intracellular signaling systems. While protein phosphorylation has long been known to modify the interactions that underlie this organization, the dynamic cycling of ...
SEAN I PATTERSON
doaj  

Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

open access: yeseLife, 2018
Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the local spatial cues into protrusive forces.
Kentarou Baba   +9 more
doaj   +1 more source

Early ontogenetic male cone production in Pinus radiata : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Plant Biology at Massey University [PDF]

open access: yes, 2000
The tree breeding industry is interested in early ontogenetic male cone production in Pinus radiata in order to maximise the rate at which successive generations can be bred.
Welsh, Shayne Kevin
core  

Induced Operators in QCD

open access: yes, 2004
Light-cone quantization always involves the solution of differential constraint equations. The solutions to these equations include integration constants (fields independent of $x_-$).
McCartor, G.
core   +1 more source

Accuracy and reproducibility of a single‐pose image‐to‐robot registration method for mobile C‐arm cone beam CT guided histotripsy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Histotripsy is a focal tumor therapy that utilizes focused ultrasound (US) to mechanically destroy tissue. To overcome visualization limitations of diagnostic US‐guidance, C‐arm cone beam CT (CBCT)‐guided histotripsy is being developed, for which a mobile C‐arm could increase accessibility. CBCT‐guided histotripsy uses a phantom with a
Grace M. Minesinger   +5 more
wiley   +1 more source

Retrograde Ret signaling controls sensory pioneer axon outgrowth

open access: yeseLife, 2019
The trafficking mechanisms and transcriptional targets downstream of long-range neurotrophic factor ligand/receptor signaling that promote axon growth are incompletely understood. Zebrafish carrying a null mutation in a neurotrophic factor receptor, Ret,
Adam Tuttle   +4 more
doaj   +1 more source

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