Results 61 to 70 of about 152,389 (315)

Posttranslational protein S-palmitoylation and the compartmentalization of signaling molecules in neurons

open access: yesBiological Research, 2002
Protein domains play a fundamental role in the spatial and temporal organization of intracellular signaling systems. While protein phosphorylation has long been known to modify the interactions that underlie this organization, the dynamic cycling of ...
SEAN I PATTERSON
doaj  

Neuronal Signaling Involved in Neuronal Polarization and Growth: Lipid Rafts and Phosphorylation

open access: yesFrontiers in Molecular Neuroscience, 2020
Neuronal polarization and growth are developmental processes that occur during neuronal cell differentiation. The molecular signaling mechanisms involved in these events in in vivo mammalian brain remain unclear.
Michihiro Igarashi   +3 more
doaj   +1 more source

Learning the Biochemical Basis of Axonal Guidance: Using Caenorhabditis elegans as a Model

open access: yesBiomedicines, 2023
Aim: Experimental models are a powerful aid in visualizing molecular phenomena. This work reports how the worm Caenorhabditis elegans (C. elegans) can be effectively explored for students to learn how molecular cues dramatically condition axonal guidance
Andreia Teixeira-Castro   +7 more
doaj   +1 more source

Geometric and dosimetric evaluation of a commercial AI auto‐contouring tool on multiple anatomical sites in CT scans

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Current radiotherapy practices rely on manual contouring of CT scans, which is time‐consuming, prone to variability, and requires highly trained experts. There is a need for more efficient and consistent contouring methods. This study evaluated the performance of the Varian Ethos AI auto‐contouring tool to assess its potential integration into
Robert N. Finnegan   +6 more
wiley   +1 more source

Revisiting Netrin-1: One Who Guides (Axons)

open access: yesFrontiers in Cellular Neuroscience, 2018
Proper patterning of the nervous system requires that developing axons find appropriate postsynaptic partners; this entails microns to meters of extension through an extracellular milieu exhibiting a wide range of mechanical and chemical properties. Thus,
Nicholas P. Boyer   +2 more
doaj   +1 more source

Cytoskeletal dynamics in growth-cone steering [PDF]

open access: yesJournal of Cell Science, 2009
Interactions between dynamic microtubules and actin filaments are essential to a wide range of cell biological processes including cell division, motility and morphogenesis. In neuronal growth cones, interactions between microtubules and actin filaments in filopodia are necessary for growth cones to make a turn.
Geraldo, Sara, Gordon-Weeks, Phillip R.
openaire   +4 more sources

Toward a human‐centric co‐design methodology for AI detection of differences between planned and delivered dose in radiotherapy

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Many artificial intelligence (AI) solutions have been proposed to enhance the radiotherapy (RT) workflow, but limited applications have been implemented to date, suggesting an implementation gap. One contributing factor to this gap is a misalignment between AI systems and their users.
Luca M. Heising   +11 more
wiley   +1 more source

Nystatin Regulates Axonal Extension and Regeneration by Modifying the Levels of Nitric Oxide

open access: yesFrontiers in Molecular Neuroscience, 2020
Nystatin is a pharmacological agent commonly used for the treatment of oral, mucosal and cutaneous fungal infections. Nystatin has also been extensively applied to study the cellular function of cholesterol-enriched structures because of its ability to ...
Cristina Roselló-Busquets   +7 more
doaj   +1 more source

Assessment of a medical physics educational program for science teachers

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction Medical physics is a fulfilling profession where physics is applied to advance human health. However, many are uninformed of the role of physicists in medicine, and students are unaware of this career pathway. This study presents a pilot 1‐year program for science teachers to learn about physics in medicine and share with students
Ashley J. Cetnar   +2 more
wiley   +1 more source

BDNF/trkB Induction of Calcium Transients through Cav2.2 Calcium Channels in Motoneurons Corresponds to F-actin Assembly and Growth Cone Formation on β2-Chain Laminin (221)

open access: yesFrontiers in Molecular Neuroscience, 2017
Spontaneous Ca2+ transients and actin dynamics in primary motoneurons correspond to cellular differentiation such as axon elongation and growth cone formation.
Benjamin Dombert   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy