Results 51 to 60 of about 1,125 (150)

A Shoot Fe Signaling Pathway Requiring the OPT3 Transporter Controls GSNO Reductase and Ethylene in Arabidopsis thaliana Roots

Frontiers in Plant Science, 2018
Ethylene, nitric oxide (NO) and glutathione (GSH) increase in Fe-deficient roots of Strategy I species where they participate in the up-regulation of Fe acquisition genes.
María J. García, Francisco J. Corpas, Carlos Lucena, Esteban Alcántara, Rafael Pérez-Vicente, Ángel M. Zamarreño, Eva Bacaicoa, José M. García-Mina, Petra Bauer, Francisco J. Romera   +9 more
doaj   +1 more source

Proteomic Analysis of S-Nitrosation Sites During Somatic Embryogenesis in Brazilian Pine, Araucaria angustifolia (Bertol.) Kuntze

Frontiers in Plant Science, 2022
Cysteine S-nitrosation is a redox-based post-translational modification that mediates nitric oxide (NO) regulation of various aspects of plant growth, development and stress responses.
Alexandre Junio Borges Araujo, Giovanni Victorio Cerruti, Rafael Zuccarelli, Marta Rodriguez Ruiz, Luciano Freschi, Ratna Singh, Bruno Maria Moerschbacher, Eny Iochevet Segal Floh, André Luis Wendt dos Santos   +8 more
doaj   +1 more source

S-nitrosoglutathione reductase (GSNOR) inhibitor as an immune modulator in experimental autoimmune encephalomyelitis [PDF]

Free Radical Biology and Medicine, 2018
We previously reported that S-nitrosoglutathione (GSNO), an endogenous nitric oxide carrier, attenuated TH17-mediated immune responses in experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS). Cellular GSNO homeostasis is regulated via its synthesis by reaction between nitric oxide and glutathione and its ...
Nishant, Saxena, Jeseong, Won, Seungho, Choi, Avtar K, Singh, Inderjit, Singh   +4 more
openaire   +2 more sources

The Metabolic Role of Mitochondria in the Perinatal Cardiac Development and Cardiovascular Diseases

Exploration, Volume 6, Issue 2, April 2026.
This review explores the critical role of mitochondria in heart development and cardiovascular disease. It highlights how mitochondrial maturation during embryonic‐to‐postnatal transition, regulated by oxygen and metabolic changes, shapes cardiac structure and function.
Minghao Li, Ruiyi Zhang, Xinyuan Li, Hefeng Huang   +3 more
wiley   +1 more source

Tomato Root Growth Inhibition by Salinity and Cadmium Is Mediated By S-Nitrosative Modifications of ROS Metabolic Enzymes Controlled by S-Nitrosoglutathione Reductase

Biomolecules, 2019
S-nitrosoglutathione reductase (GSNOR) exerts crucial roles in the homeostasis of nitric oxide (NO) and reactive nitrogen species (RNS) in plant cells through indirect control of S-nitrosation, an important protein post-translational modification in ...
Tereza Jedelská, Veronika Šmotková Kraiczová, Lucie Berčíková, Lucie Činčalová, Lenka Luhová, Marek Petřivalský   +5 more
doaj   +1 more source

S-nitrosation in endothelium: different outcomes of NRF2 and GSNOR loss

Free Radical Biology and Medicine
Cardiovascular diseases are a major global health burden, and that is largely caused by premature aging of endothelial cells (ECs). Therefore, understanding of molecular mechanisms of EC aging is central to establishing novel therapeutic approaches. We have previously found that cells devoid of the transcription factor NRF2 are prematurely aged and ...
Aleksandra Kopacz, Damian Kloska, Izabela Kraszewska, Marta Targosz-Korecka, Agata Kubisiak, Urszula Jankowska, Bozena Skupien-Rabian, Anna Grochot-Przeczek, Alicja Jozkowicz   +8 more
openaire   +3 more sources

Effect of Seed Priming by Zinc‐Ion and Zinc‐Oxide Nanoparticle Enriched Plasma‐Activated Water in Osmotic‐Stressed Arabidopsis thaliana

Plasma Processes and Polymers, Volume 23, Issue 4, April 2026.
Plasma treatment with metallic Zn stabilizes nitrite, while ZnO nanoparticles favour for nitrite oxidation. PAW seed priming alters seed coat, increases K⁺ efflux, improves germination, and enhances Zn uptake. Under osmotic stress, seedlings show higher NO levels, with improved cotyledon growth and stomatal formation, strengthening early stress ...
Tamás Bodor, Gábor Fejes, Nicole Chaumont, Christophe Bailly, Ádám Solti, Maria Gracheva, Imre Szenti, Zoltán Kónya, Andrea Rónavári, Kinga Kutasi, Zsuzsanna Kolbert   +10 more
wiley   +1 more source

Structural and functional insights into nitrosoglutathione reductase from Chlamydomonas reinhardtii

Redox Biology, 2021
Protein S-nitrosylation plays a fundamental role in cell signaling and nitrosoglutathione (GSNO) is considered as the main nitrosylating signaling molecule.
Andrea Tagliani, Jacopo Rossi, Christophe H. Marchand, Marcello De Mia, Daniele Tedesco, Libero Gurrieri, Maria Meloni, Giuseppe Falini, Paolo Trost, Stéphane D. Lemaire, Simona Fermani, Mirko Zaffagnini   +11 more
doaj   +1 more source

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source

Increased Nitrosoglutathione Reductase Activity in Hypoxic Pulmonary Hypertension in Mice

Journal of Pharmacological Sciences, 2010
Altered S-nitrosothiols (RSNO) signaling is linked to pulmonary hypertension. Recent studies have shown that S-nitrosoglutathione (GSNO) reductase (GSNOR) catalyzes the degradation of GSNO and indirectly regulates the level of RSNO in vivo.
Xiling Wu, Lizhong Du, Xuefeng Xu, Linhua Tan, Ruyi Li   +4 more
doaj   +1 more source