Results 41 to 50 of about 1,125 (150)

S-Nitrosothiol Signaling Regulates Liver Development and Improves Outcome following Toxic Liver Injury

Cell Reports, 2014
Toxic liver injury is a leading cause of liver failure and death because of the organ’s inability to regenerate amidst massive cell death, and few therapeutic options exist.
Andrew G. Cox, Diane C. Saunders, Peter B. Kelsey Jr., Allie A. Conway, Yevgenia Tesmenitsky, Julio F. Marchini, Kristin K. Brown, Jonathan S. Stamler, Dorothy B. Colagiovanni, Gary J. Rosenthal, Kevin J. Croce, Trista E. North, Wolfram Goessling   +12 more
doaj   +1 more source

Strigolactones Interact With Nitric Oxide in Regulating Root System Architecture of Arabidopsis thaliana

Frontiers in Plant Science, 2020
Both nitric oxide (NO) and strigolactone (SL) are growth regulating signal components in plants; however, regarding their possible interplay our knowledge is limited.
Dóra Oláh, Gábor Feigl, Árpád Molnár, Attila Ördög, Zsuzsanna Kolbert   +4 more
doaj   +1 more source

Analysis of NIA and GSNOR family genes and nitric oxide homeostasis in response to wheat-leaf rust interaction

Scientific Reports, 2022
Nitric oxide (NO) modulates plant response to biotic and abiotic stresses by S-nitrosylation-mediated protein post-translational modification. Nitrate reductase (NR) and S-nitrosoglutathione reductase (GSNOR) enzymes are essential for NO synthesis and ...
Deepak T. Hurali, Ramesh Bhurta, Sandhya Tyagi, Lekshmy Sathee, Adavi B. Sandeep, Dalveer Singh, Niharika Mallick, Vinod, Shailendra K. Jha   +8 more
doaj   +1 more source

S-Nitrosoglutathione Reductase Plays Opposite Roles in SH-SY5Y Models of Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Mediators of Inflammation, 2015
Oxidative and nitrosative stresses have been reported as detrimental phenomena concurring to the onset of several neurodegenerative diseases. Here we reported that the ectopic modulation of the denitrosylating enzyme S-nitrosoglutathione reductase (GSNOR)
Salvatore Rizza, Claudia Cirotti, Costanza Montagna, Simone Cardaci, Claudia Consales, Mauro Cozzolino, Maria Teresa Carrì, Francesco Cecconi, Giuseppe Filomeni   +8 more
doaj   +1 more source

The Physiological Implications of S-Nitrosoglutathione Reductase (GSNOR) Activity Mediating NO Signalling in Plant Root Structures

Antioxidants, 2020
Nitrogen remains an important macronutrient in plant root growth due to its application in amino acid production, in addition to its more elusive role in cellular signalling through nitric oxide (NO).
Leslie Ventimiglia, Bulent Mutus
doaj   +1 more source

Cyst Nematode Infection Elicits Alteration in the Level of Reactive Nitrogen Species, Protein S-Nitrosylation and Nitration, and Nitrosoglutathione Reductase in Arabidopsis thaliana Roots

Antioxidants, 2020
Reactive nitrogen species (RNS) are redox molecules important for plant defense against pathogens. The aim of the study was to determine whether the infection by the beet cyst nematode Heterodera schachtii disrupts RNS balance in Arabidopsis thaliana ...
Mateusz Labudda, Elżbieta Różańska, Marta Gietler, Justyna Fidler, Ewa Muszyńska, Beata Prabucka, Iwona Morkunas   +6 more
doaj   +1 more source

Pharmacological Inhibition of Class III Alcohol Dehydrogenase 5: Turning Remote Ischemic Conditioning Effective in a Diabetic Stroke Model

Antioxidants, 2022
The restoration of cerebral blood flow (CBF) to achieve brain tissue oxygenation (PbtO2) is the primary treatment for ischemic stroke, a significant cause of adult mortality and disability worldwide.
Syed Kashif Zaidi, Md Nasrul Hoda, Shams Tabrez, Mohammad Imran Khan   +3 more
doaj   +1 more source

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

Advanced Science, Volume 13, Issue 23, 23 April 2026.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi, Navatha Shree Sharma, Imran Ibn Gani Rather, S. M. Shatil Shahriar, Jingwei Xie   +4 more
wiley   +1 more source

GSNOR overexpression enhances CAR-T cell stemness and anti-tumor function by enforcing mitochondrial fitness [PDF]

Molecular Therapy
Qing Niu, Xiaoming Feng, Mingxia Shi
exaly   +2 more sources

S-Nitrosoglutathione Reductase—The Master Regulator of Protein S-Nitrosation in Plant NO Signaling

Plants, 2019
S-nitrosation has been recognized as an important mechanism of protein posttranslational regulations, based on the attachment of a nitroso group to cysteine thiols.
Jana Jahnová, Lenka Luhová, Marek Petřivalský   +2 more
doaj   +1 more source