Results 11 to 20 of about 5,738,873 (283)
Myc and Fgf Are Required for Zebrafish Neuromast Hair Cell Regeneration. [PDF]
PLoS ONE, 2016 Unlike mammals, the non-mammalian vertebrate inner ear can regenerate the sensory cells, hair cells, either spontaneously or through induction after hair cell loss, leading to hearing recovery.
Sang Goo Lee +11 more
doaj +2 more sources
Sensory hair cell death and regeneration [PDF]
Frontiers in Cellular Neuroscience, 2016 Sensory hair cells are the specialized mechanosensory receptors found in vertebrate auditory, vestibular, and lateral line organs that transduce vibratory and acoustic stimuli into the sensations of hearing and balance.
Michael E. Smith +4 more
core +5 more sources
The Transcriptomics to Proteomics of Hair Cell Regeneration: Looking for a Hair Cell in a Haystack [PDF]
Microarrays, 2013 Mature mammals exhibit very limited capacity for regeneration of auditory hair cells, while all non-mammalian vertebrates examined can regenerate them. In an effort to find therapeutic targets for deafness and balance disorders, scientists have examined ...
Gopinath Rajadinakaran, Michael Smith
core +5 more sources
Development and regeneration of hair cells
Acta Oto-Laryngologica, 2007 The vertebrate inner ear is derived from the otic placode and undergoes a complicated series of morphogenetic processes to differentiate into an elaborate structure harboring mechanosensory epithelia featuring hair cells, the mechanoreceptors of hearing ...
Kaga, Kimitaka +4 more
core +3 more sources
Regeneration of Hair Cells in the Human Vestibular System
Frontiers in Molecular Neuroscience, 2022 The vestibular system is a critical part of the human balance system, malfunction of this system will lead to balance disorders, such as vertigo. Mammalian vestibular hair cells, the mechanical receptors for vestibular function, are sensitive to ototoxic
Yikang Huang +5 more
doaj +3 more sources
Characterization of the Transcriptome of Hair Cell Regeneration in the Neonatal Mouse Utricle [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Hearing and balance deficits are mainly caused by loss of sensory inner ear hair cells. The key signals that control hair cell regeneration are of great interest.
Jinghong Han +6 more
doaj +2 more sources
Current Opinion in Neurobiology, 2008 The mammalian inner ear largely lacks the capacity to regenerate hair cells, the sensory cells required for hearing and balance. Recent studies in both lower vertebrates and mammals have uncovered genes and pathways important in hair cell development and have suggested ways that the sensory epithelia could be manipulated to achieve hair cell ...
Albert Sb, Edge, Zheng-Yi, Chen
openaire +2 more sources
Neural Cell Adhesion Molecule Ncam1b Promotes Effective Hair Cell Regeneration in Zebrafish Neuromasts. [PDF]
Int J Mol SciThis study examines the distinct roles of the neural cell adhesion molecules Ncam1a and Ncam1b in zebrafish neuromasts during both homeostasis and hair cell regeneration.
Lange A +3 more
europepmc +2 more sources
The role of epigenetic modifications in sensory hair cell development, survival, and regulation
Frontiers in Cellular Neuroscience, 2023 The cochlea is the sensory organ in the periphery, and hair cells are its main sensory cells. The development and survival of hair cells are highly controlled processes.
Ying Xiao, Dan Li
doaj +1 more source
Regulation and dysregulation of hair regeneration: aiming for clinical application
Cell Regeneration, 2022 Hair growth and regeneration represents a remarkable example of stem cell function. Recent progress emphasizes the micro- and macro- environment that controls the regeneration process.
Zhicao Yue +4 more
doaj +1 more source