C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient.
PLoS ONE, 2021 Hearing depends on the transduction of sounds into neural signals by the inner hair cells of the cochlea. Cochleae also have outer hair cells with unique electromotile properties that increase auditory sensitivity, but they are particularly susceptible ...
Joyshree Biswas +8 more
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Short-term synaptic plasticity regulates the level of olivocochlear inhibition to auditory hair cells [PDF]
, 2011 In the mammalian inner ear, the gain control of auditory inputs is exerted by medial olivocochlear (MOC) neurons that innervate cochlear outer hair cells (OHCs).
Ballestero, Jimena Andrea +5 more
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Regenerated Synapses Between Postnatal Hair Cells and Auditory Neurons [PDF]
Journal of the Association for Research in Otolaryngology, 2013 Regeneration of synaptic connections between hair cells and spiral ganglion neurons would be required to restore hearing after neural loss. Here we demonstrate by immunohistochemistry the appearance of afferent-like cochlear synapses in vitro after co-culture of de-afferented organ of Corti with spiral ganglion neurons from newborn mice.
Mingjie, Tong +2 more
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Artificial induction of Sox21 regulates sensory cell formation in the embryonic chicken inner ear.
PLoS ONE, 2012 During embryonic development, hair cells and support cells in the sensory epithelia of the inner ear derive from progenitors that express Sox2, a member of the SoxB1 family of transcription factors.
Stephen D Freeman, Nicolas Daudet
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Mechanisms of synaptic depression at the hair cell ribbon synapse that support auditory nerve function [PDF]
, 2017 Inner hair cells (IHCs) in the cochlea are the mammalian phono-receptors, transducing sound energy into graded changes in membrane potentials, the so called “receptor potentials.” Ribbon synapses between IHCs and auditory nerve neurons are responsible ...
Goutman, Juan Diego
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IBRO Neuroscience Reports, 2022 Studies by His from 1868 to 1904 delineated the critical role of the dorsal roof plate in the development of the hindbrain choroid plexus, and of the rhombic lips in the development of hindbrain auditory centers.
Joel C. Glover, Bernd Fritzsch
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Mammalian cochlea as a physics guided evolution-optimized hearing sensor [PDF]
, 2014 Nonlinear physics plays an essential role in hearing, from sound signal generation to sound sensing to the processing of complex sound environments. We demonstrate that the evolution of the biological hearing sensors demonstrates a dramatic reduction in ...
Gomez, Florian +2 more
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Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear [PDF]
, 2018 It has recently been shown that the oxygen-regulated factors erythropoietin (Epo) and vascular endothelial growth factor (VEGF) confer protection on different cells, including neuronal-derived ones.
Bodmer, Daniel +2 more
core
Quantitative Analysis Linking Inner Hair Cell Voltage Changes and Postsynaptic Conductance Change: A Modelling Study [PDF]
, 2015 This paper presents a computational model which estimates the postsynaptic conductance change of mammalian Type I afferent peripheral process when airborne acoustic waves impact on the tympanic membrane. A model of the human auditory periphery is used to
Drakakis, EM, Prokopiou, AN
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A deep learning approach to quantify auditory hair cells
Hearing Research, 2021 StarDist 2D deep learning model and training dataset.
Maurizio Cortada +4 more
openaire +2 more sources