Results 1 to 10 of about 24,267 (230)

CNTN2 Deficiency Disrupts Ascending Auditory Neuroglial Interactions and Redox Homeostasis in Neural Presbycusis. [PDF]

Adv Sci (Weinh)
. ABSTRACT Neural presbycusis disrupts auditory timing and speech perception, yet its molecular basis remains poorly understood. This study identifies Cntn2 as the Ranvier's nodal molecule significantly downregulated in aged auditory nerves. Cntn2 heterozygous knockout (Cntn2+/−) mice showed elevated auditory brainstem response thresholds and prolonged
Chen P, Zhu J, Huang S, Xu B, Duan M, Lv J, Chen J, Yang J, Hou S.   +8 more
europepmc   +2 more sources

Targeting TRP channels in hearing loss from mechanisms to otoprotection. [PDF]

iScience
Yang Y, Li S, Xie L, Li J, Wang C, Li Z, Li Y.   +6 more
europepmc   +1 more source

Integrating Regenerative Medicine and Stem Cell Therapy in Hearing Restoration: A Systematic Review. [PDF]

Cureus
Hussain ID, Tanveer H, Hussain MA, Rashid H, Salah O, Khalil H.   +5 more
europepmc   +1 more source

Emerging Therapies for Genetic Deafness: The Rise of Precision Gene Editing. [PDF]

Ear Hear
Lahlou G, Cornille M, Lai N, Lecomte MJ, Safieddine S.   +4 more
europepmc   +1 more source

Inhibition of aberrant astrocyte activity restores auditory sensorimotor function in zebrafish <i>spen</i> mutants. [PDF]

Sci Adv
Gao Y, Shipman A, Sun P, Zhang N, Smith ET, Pacentine I, Nechiporuk A, Nicolson T.   +7 more
europepmc   +1 more source

Comorbid Auditory and Visual Dysfunction: From Pathogenic Genes to Gene Therapy. [PDF]

Genes (Basel)
Hu J, Kong C, Sun Y.
europepmc   +1 more source

Exposure-duration-associated auditory dysfunction and cochlear presynaptic ribbon alterations during simulated high-altitude hypobaric hypoxia in mice. [PDF]

Front Neurol
Zhang Q, Yue G, Zhang Y, Li S, Cao W, Zhang X, Ren B, Zhang C, Wang C, Chen W, Wuren T, Guo B, Wang Y.   +12 more
europepmc   +1 more source

HDAC1 Represses NRF2 Transcription via H3K27ac Remodeling to Aggravate Neomycin-Induced Cochlear Hair Cell Damage. [PDF]

Neurochem Res
Gong S, Cao X, Jia L, Li S, Cha W, Chen S.   +5 more
europepmc   +1 more source

Photobiomodulation as a Potential Regenerative Signal in the Inner Ear: Linking Mitochondrial Redox Signaling to Cell-Fate Regulation. [PDF]

Int J Mol Sci
Lee MY.
europepmc   +1 more source

Advances and prospects of 3D air-liquid interface cultured middle ear epithelial cells and inner ear organoids in otologic diseases. [PDF]

Front Bioeng Biotechnol
Gu L, Du M, Zhang K, Wu Y, Zheng T, Zheng Q, Li B.   +6 more
europepmc   +1 more source