Results 71 to 80 of about 22,677 (167)

Therapeutic potential of stem cells in auditory hair cell repair

Journal of Stem Cells and Regenerative Medicine, 2009
The prevalence of acquired hearing loss is very high. About 10% of the total population and more than one third of the population over 65 years suffer from debilitating hearing loss.
Ryuji Hata
doaj  

Endolymphatic hydrops and cochlear synaptopathy after noise exposure are distinct sequelae of hair cell stereociliary bundle trauma

Scientific Reports
Endolymphatic hydrops, increased endolymphatic fluid within the cochlea, is the key pathologic finding in patients with Meniere’s disease, a disease of episodic vertigo, fluctuating hearing loss, tinnitus, and aural fullness.
Michelle L. Fong, Connie B. Paik, Patricia M. Quiñones, Clayton B. Walker, Michael J. Serafino, Dorothy W. Pan, Eduardo Martinez, Juemei Wang, Grady W. Phillips, Brian E. Applegate, Michael Anne Gratton, John S. Oghalai   +11 more
doaj   +1 more source

Baicalin attenuates cisplatin-induced cochlear hair cell damage by modulating the ROS-p38 MAPK signaling pathway. [PDF]

Front Cell Dev Biol
Zhang Q, Wang Y, Zhang C, Li S, Yin Q, Zhou C, Dong C, Bu C.   +7 more
europepmc   +1 more source

Genetic and Environmental Factors Shaping Hearing Loss: Xenobiotics, Mechanisms and Translational Perspectives. [PDF]

J Xenobiot
Esteves F, Caria H.
europepmc   +1 more source

Quercetin prevents age-related hearing loss in C57BL/6J mice by activating mitophagy and inhibiting the NLRP3 inflammasome. [PDF]

PLoS One
Feng M, Zhou X, Yang T, Chen Z, Yang G, Jiang X, Yuan W.   +6 more
europepmc   +1 more source

Cochlear macrophage CD74 enhances the apoptosis of senescent cochlear hair cells by down-regulating MIF. [PDF]

Front Immunol
Sun XM, Sun QY, Zhao MQ, Wen WP, Wei FQ.
europepmc   +1 more source

Abnormal iron homeostasis mediates cochlear hair cell impairment and hearing loss in Gprasp2-deficient mice. [PDF]

Commun Biol
Lu Y, Sheng F, Yao J, Wei Q, Chen H, Chen Z, Xing G, Cao X, Wang T.   +8 more
europepmc   +1 more source

Cochlear Amplification Modulates Synaptic Transmission at the Endbulb of Held Synapse in the Cochlear Nucleus. [PDF]

J Neurosci
Wang F, Li Y, Li GL.
europepmc   +1 more source

Fluoxetine minimally affects hearing loss but induces gene expression changes in the cochlear nuclei after noise exposure. [PDF]

PLoS One
An HJ, Choi S, Lee S, Yeo H, Kim SY.
europepmc   +1 more source

Histopathology of Inner Ear Malformations: Potential Prognostic Factors and Their Influence in the Decision-Making Between CI and ABI. [PDF]

J Otolaryngol Head Neck Surg
Sennaroglu L, Monsanto RDC, Lee DJ, Sancak IG, Paparella MM, Cureoglu S.   +5 more
europepmc   +1 more source