Results 121 to 130 of about 6,486 (158)
The Unexplored Role of Connexin Hemichannels in Promoting Facioscapulohumeral Muscular Dystrophy Progression. [PDF]
Int J Mol SciDíaz-Ubilla M, Retamal MA.
europepmc +1 more source
Following Tracks of Hemichannels [PDF]
Cell Communication and Adhesion, 2003 It has been suggested that plasma membrane-bound hemichannels perform physiological and pathophysiological functions per se. Such functions require the presence of hemichannels on the cell surface and their accessibility to the extracellular environment for at least some limited period of time.
Rolf Dermietzel +2 more
exaly +4 more sources
Connexin hemichannels and cochlear function [PDF]
Neuroscience Letters, 2019 Connexins play vital roles in hearing, including promoting cochlear development and sustaining auditory function in the mature cochlea. Mutations in connexins expressed in the cochlear epithelium, Cx26 and Cx30, cause sensorineural deafness and in the case of Cx26, is one of the most common causes of non-syndromic, hereditary deafness.
Vytas K Verselis
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Gap junctional hemichannels in the heart
Acta Physiologica Scandinavica, 2003AbstractUpon contacting each other, cells form gap junctions, in which each cell contributes half of the channel linking their cytoplasms, enabling them to share their metabolome up to a molecular weight of 1000. Each hemichannel (or connexon) is randomly inserted into the plasma membrane and then migrates to the site of cell‐to‐cell contact before ...
J N Weiss
exaly +3 more sources
Hemichannels in Cerebral Ischemia
Current Molecular Medicine, 2009Hemichannels are transmembrane channels that represent the functional subunits of gap junctions. Each hemichannel is composed of a connexin or pannexin hexamer and, after being transported to the membrane, remains unpaired until it is incorporated in a gap junction. Several studies have already provided evidence that gap junction-mediated intercellular
Panagiotis, Bargiotas +2 more
openaire +2 more sources
Connexin hemichannel inhibitors with a focus on aminoglycosides
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2021Connexins are membrane proteins involved directly in cell-to-cell communication through the formation of gap-junctional channels. These channels result from the head-to-head docking of two hemichannels, one from each of two adjacent cells. Undocked hemichannels are also present at the plasma membrane where they mediate the efflux of molecules that ...
Cristina M, Natha +4 more
openaire +2 more sources
Hemichannel-Mediated Inhibition in the Outer Retina
Science, 2001An essential feature of the first synapse in the retina is a negative feedback pathway from horizontal cells to cones. Here we show that at this synapse, connexin26 forms hemichannels on horizontal cell dendrites near the glutamate release site of the cones. Blocking these hemichannels hyperpolarizes horizontal cells, modulates the Ca
Kamermans, M. +5 more
openaire +2 more sources
Biophysical characterization of zebrafish connexin35 hemichannels
American Journal of Physiology-Cell Physiology, 2004A subset of connexins can form unopposed hemichannels in expression systems, providing an opportunity for comparison of hemichannel gating properties with those of intact gap junction channels. Zebrafish connexin35 (Cx35) is a member of the Cx35/Cx36 subgroup of connexins highly expressed in the retina and brain.
Virginijus, Valiunas +5 more
openaire +2 more sources
Hemichannels: New pathways for gliotransmitter release
Neuroscience, 2015Growing evidence suggests that glial cells express virtually all known types of neurotransmitter receptors, enabling them to sense neuronal activity and microenvironment changes by responding locally via the Ca(2+)-dependent release of bioactive molecules, known as "gliotransmitters".
Montero, T.D. +1 more
openaire +3 more sources