Results 121 to 130 of about 465,990 (261)
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. [PDF]
, 2013 Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Dykstra, Andrew B +2 more
core +2 more sources
A Mechanistic Model of Annual Sulfate Concentrations in the United States [PDF]
arXiv, 2020 We develop a mechanistic model to analyze the impact of sulfur dioxide emissions from coal-fired power plants on average sulfate concentrations in the central United States. A multivariate Ornstein-Uhlenbeck (OU) process is used to approximate the dynamics of the underlying space-time chemical transport process, and its distributional properties are ...
arxiv
Structure of glassy lithium sulfate films sputtered in nitrogen (LISON): Insight from Raman spectroscopy and ab initio calculations [PDF]
, 2007 Raman spectra of thin solid electrolyte films obtained by sputtering a lithium sulfate target in nitrogen plasma are measured and compared to ab initio electronic structure calculations for clusters composed of 28 atoms. Agreement between measured and calculated spectra is obtained when oxygen atoms are replaced by nitrogen atoms and when the nitrogen ...
arxiv +1 more source
Demystifying heparan sulfate-protein interactions.
Annual Review of Biochemistry, 2014 Numerous proteins, including cytokines and chemokines, enzymes and enzyme inhibitors, extracellular matrix proteins, and membrane receptors, bind heparin.
Ding Xu, J. Esko
semanticscholar +1 more source
Biotechnology Progress, EarlyView.Abstract Recombinant adeno‐associated virus (rAAV) is a widely used delivery vehicle in gene therapy. A scalable production technology is essential for its wide clinical applications. We have taken a synthetic biology approach to generate HEK293‐based cell lines which harbor integrated genetic elements encoding essential AAV and adenoviral helper ...
Han‐Jung Kuo +6 more
wiley +1 more source
A monoclonal antibody against a laminin-heparan sulfate proteoglycan complex perturbs cranial neural crest migration in vivo [PDF]
, 1988 INO (inhibitor of neurite outgrowth) is a monoclonal antibody that blocks axon outgrowth, presumably by functionally blocking a laminin-heparan sulfate proteoglycan complex (Chiu, A. Y., W. D. Matthew, and P. H. Patterson. 1986. J. Cell Biol.
Bronner-Fraser, Marianne +1 more
core +2 more sources
Heparan sulfate proteoglycans: a sugar code for vertebrate development?
Development, 2015 Heparan sulfate proteoglycans (HSPGs) have long been implicated in a wide range of cell-cell signaling and cell-matrix interactions, both in vitro and in vivo in invertebrate models.
Fabienne E. Poulain, H. Joseph Yost
semanticscholar +1 more source
Developmental Dynamics, EarlyView.Abstract Background Longitudinal skeletal growth takes place in the cartilaginous growth plates. While growth plates are found at either end of conventional long bones, they occur at a variety of locations in the mammalian skeleton. For example, the metacarpals and metatarsals (MT) in the hands and feet form only a single growth plate at one end, and ...
Philip L. Reno +4 more
wiley +1 more source
Ligand-induced Coupling versus Receptor Pre-association: Cellular automaton simulations of FGF-2 binding [PDF]
J. Theor. Biol. 227(2) 239-251 (2004), 2003 The binding of basic fibroblast growth factor (FGF-2) to its cell surface receptor (CSR) and subsequent signal transduction is known to be enhanced by Heparan Sulfate Proteoglycans (HSPGs). HSPGs bind FGF-2 with low affinity and likely impact CSR-mediated signaling via stabilization of FGF-2-CSR complexes via association with both the ligand and the ...
arxiv
Diverse Roles of Heparan Sulfate and Heparin in Wound Repair
BioMed Research International, 2015 Heparan sulfate (HS) and heparin (Hp) are linear polysaccharide chains composed of repeating (1→4) linked pyrosulfuric acid and 2-amino-2-deoxy glucopyranose (glucosamine) residue.
P. Olczyk +2 more
semanticscholar +1 more source