Results 151 to 160 of about 84,900 (313)

Heparan Sulfate Proteoglycans in Infection

open access: yes, 2011
To cause infections, microbial pathogens elaborate a multitude of factors that interact with host components. Using these host–pathogen interactions to their advantage, pathogens attach, invade, disseminate, and evade host defense mechanisms to promote their survival in the hostile host environment.
Pyong Woo Park, Allison H. Bartlett
openaire   +2 more sources

Status quo and future developments in the diagnosis and treatment of hereditary angioedema

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Hereditary angioedema (HAE) is a rare hereditary disease characterized by edema, which can be life‐threatening in case of swelling in the larynx. The most common form of HAE is caused by a mutation of the SERPING1 gene and is characterized by a deficiency (type I) or loss of function (type II) of the C1 inhibitor (C1‐INH), leading to excessive ...
Andreas Recke
wiley   +1 more source

Origin and deposition of basement membrane heparan sulfate proteoglycan in the developing intestine. [PDF]

open access: bronze, 1989
Patricia Simon‐Assmann   +3 more
openalex   +1 more source

Osteochondrosis in horses: An overview of genetic and other factors

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Osteochondrosis (OC) is a frequent manifestation of developmental orthopaedic disease, and its severe clinical presentation is known as OC dissecans (OCD). OC is defined as a disruption of the endochondral ossification process in the epiphyseal cartilage, and this disease has been reported in different mammalian species, including humans, dogs,
Lola Martinez‐Saez   +2 more
wiley   +1 more source

Principal mechanisms of extracellular matrix‐mediated cell–cell communication in physiological and tumor microenvironments

open access: yesThe FEBS Journal, EarlyView.
Intracellular communication controls the processing of generated signals so that every cell type can successfully respond. The extracellular matrix (ECM) is a fundamental regulator of cell communication and signaling through the strict orchestration and functions of its bioactive components.
Zoi Piperigkou   +6 more
wiley   +1 more source

Heparan sulfate proteoglycans of human lung fibroblasts. Occurrence of distinct membrane, matrix and secreted forms [PDF]

open access: bronze, 1986
V Lories   +3 more
openalex   +1 more source

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

open access: yes, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +1 more source

N‐terminal helix formation and dimer–monomer transition of FGF10 in specific recognition of FGFR2b

open access: yesThe FEBS Journal, EarlyView.
FGF10 specifically recognizes FGFR2b with a conformational change of the N‐terminal part. The N‐terminal part of FGF10 and two loops of FGFR2b constituting the interaction interface are the most varied regions in FGF and FGFR family members. FGF10 shows a concentration‐dependent dimerization.
Hyunjae Park   +12 more
wiley   +1 more source

CLEC18A interacts with sulfated glycosaminoglycans and controls clear cell renal cell carcinoma progression

open access: yesThe FEBS Journal, EarlyView.
CLEC18A is a previously poorly characterized C‐type lectin. We mapped the expression of CLEC18A to the proximal tubule of the kidney and found CLEC18A to interact with sulfated glycosaminoglycans on proteoglycans. Furthermore, we found that CLEC18A plays an important role in hindering the progression of clear cell renal cell carcinomas in humans and in
Gustav Jonsson   +10 more
wiley   +1 more source

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