Results 181 to 190 of about 84,900 (313)

Immunomodulatory Mechanisms of Chronic Wound Healing: Translational and Clinical Relevance

open access: yesMedComm, Volume 6, Issue 11, November 2025.
This graphical abstract illustrates the immunomodulation of chronic wounds through various therapeutic approaches aimed at regulating the immune response to promote healing. ABSTRACT Chronic wounds—such as diabetic foot ulcers (DFUs), pressure ulcers (PUs), and venous leg ulcers (VLUs)—pose a serious clinical challenge due to their prolonged ...
Mahrukh Riaz   +3 more
wiley   +1 more source

Regulated Diversity of Heparan Sulfate [PDF]

open access: yesJournal of Biological Chemistry, 1998
Marion Kusche-Gullberg   +2 more
openaire   +3 more sources

Evaluation of Endothelial Glycocalyx Damage in Neonatal Lambs With Diarrhoea: A Biomarker‐Based Approach

open access: yesVeterinary Medicine and Science, Volume 11, Issue 6, November 2025.
Neonatal lambs with diarrhoea showed increased nitric oxide and decreased heparan sulphate and angiopoietin‐2 levels, suggesting preserved endothelial glycocalyx integrity. Elevated ADAM15 levels in E. coli cases indicate a pathogen‐specific endothelial response, highlighting nitric oxide's potential protective role during inflammation.
Murat Kaan Durgut   +7 more
wiley   +1 more source

The Role of Heparan Sulfate in Bone Repair and Regeneration. [PDF]

open access: yesCalcif Tissue Int
Li Y, Zheng L, Cheng W, Hou B, Wong RCW.
europepmc   +1 more source

Mucopolysaccharidosis Type IIIB With Pancytopenia: A Case Report and Hematological Correlations in Mice

open access: yesClinical Genetics, Volume 108, Issue 5, Page 604-608, November 2025.
We report an individual with mucopolysaccharidosis type IIIB and chronic pancytopenia. Hematological studies in a mouse model revealed microcytic anemia and decreased monocyte count. Hence, pancytopenia is thought to be secondary to mucopolysaccharidosis type IIIB, and we suggest that a complete blood count should be included in the clinical ...
Éliane Beauregard‐Lacroix   +3 more
wiley   +1 more source

Decoding Glycosylation in Neurodegenerative Diseases: Mechanistic Insights and Therapeutic Opportunities

open access: yesThe FASEB Journal, Volume 39, Issue 20, 31 October 2025.
Graphical summary of glycosylation impairments in various neurodegenerative disorders. Among the diverse forms of glycosylation, the most extensively studied include N‐glycosylation, O‐glycosylation, and O‐GlcNAcylation. Aberrant glycosylation has been implicated in multiple neurodegenerative conditions.
Haihan Yu   +5 more
wiley   +1 more source

Interaction of aminoglycosides with heparan sulfate from rat kidney.

open access: bronze, 1987
Yukihiko Aramaki   +3 more
openalex   +2 more sources

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