Results 181 to 190 of about 475,440 (346)
Heparan sulfate proteoglycan and laminin immunoreactivity on cultured astrocytes: relationship to differentiation and neurite growth [PDF]
MD Ard, RP Bunge
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Conjugating a tri‐nitrilotriacetic acid unit to quinoline‐based cyanine dyes generated probes that fluoresce upon binding to His‐tagged proteins on cell surfaces. Using the thiazole orange‐bearing probe, the binding of the receptor binding domain (RBD) of the SARS‐CoV‐2 virus to host cells is readily detected, enabling the straightforward ...
Pragati Kishore Prasad+18 more
wiley +1 more source
The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition
Six genes involved in the heparan sulfate and heparin metabolism pathway, DSEL (dermatan sulfate epimerase-like), EXTL1 (exostoses (multiple)-like 1), HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), HS6ST3 (heparan sulfate 6-O-sulfotransferase 3), NDST3
Zhihua Jiang, Jennifer J. Michal, Xiao-Lin Wu, Zengxiang Pan, Michael D. MacNeil
doaj
Polysialosides Outperform Sulfated Analogs for Binding with SARS‐CoV‐2
Both sulfated and sialylated glycans present on the cell surface act as co‐receptors for the SARS‐CoV‐2 attachment. Polysialylated and sulfated dendritic polyglycerols are studied for their binding with SARS‐CoV‐2. In solution, dendritic polyglycerol sialosides (dPGSAs) bind significantly stronger (low nm) to SARS‐CoV‐2 than their sulfated analogs ...
Vinod Khatri+16 more
wiley +1 more source
Objective: Various enzymes, reactive oxygen species, inflammatory conditions, and major surgeries cause endothelial glycocalyx breakdown. Inhalation of anaesthetic agents may have protective effects on the endothelium.
Kemal Tolga Saraçoğlu+8 more
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Origin and deposition of basement membrane heparan sulfate proteoglycan in the developing intestine. [PDF]
Patricia Simon‐Assmann+3 more
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Bioactive Polysulfate‐Based Nano‐Assemblies Against Virus Infection
Nano‐assemblies with a defined brush‐like corona are developed from sulfated polyglycerol to inhibit virus infection. The sulfate residues on the surface can actively bind the virus and entrap it from entering the host cells. This nanosystem is demonstrated potent inhibition against both HSV‐1 and SARs‐CoV‐2.
Guoxin Ma+9 more
wiley +1 more source
Heterogeneous distribution of a basement membrane heparan sulfate proteoglycan in rat tissues. [PDF]
John Couchman
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Proteoglycans on the cell surface can exhibit a baffling diversity of structures, but the relative importance of that diversity in controlling the specificity of interactions between proteins is not known. On page 845, Allen et al. demonstrate that heparan sulfate serves as a tissue-specific regulator of interactions between FGF family members and FGF ...
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