Results 181 to 190 of about 475,440 (346)

Low‐Background His‐Tag‐Targeting Probes for Turn‐On Fluorescence Detection of Cell Surface Proteins and Their Binding Interactions

open access: yesSmall, EarlyView.
Conjugating a tri‐nitrilotriacetic acid unit to quinoline‐based cyanine dyes generated probes that fluoresce upon binding to His‐tagged proteins on cell surfaces. Using the thiazole orange‐bearing probe, the binding of the receptor binding domain (RBD) of the SARS‐CoV‐2 virus to host cells is readily detected, enabling the straightforward ...
Pragati Kishore Prasad   +18 more
wiley   +1 more source

The Heparan and Heparin Metabolism Pathway is Involved in Regulation of Fatty Acid Composition

open access: yesInternational Journal of Biological Sciences, 2011
Six genes involved in the heparan sulfate and heparin metabolism pathway, DSEL (dermatan sulfate epimerase-like), EXTL1 (exostoses (multiple)-like 1), HS6ST1 (heparan sulfate 6-O-sulfotransferase 1), HS6ST3 (heparan sulfate 6-O-sulfotransferase 3), NDST3
Zhihua Jiang, Jennifer J. Michal, Xiao-Lin Wu, Zengxiang Pan, Michael D. MacNeil
doaj  

Polysialosides Outperform Sulfated Analogs for Binding with SARS‐CoV‐2

open access: yesSmall, EarlyView.
Both sulfated and sialylated glycans present on the cell surface act as co‐receptors for the SARS‐CoV‐2 attachment. Polysialylated and sulfated dendritic polyglycerols are studied for their binding with SARS‐CoV‐2. In solution, dendritic polyglycerol sialosides (dPGSAs) bind significantly stronger (low nm) to SARS‐CoV‐2 than their sulfated analogs ...
Vinod Khatri   +16 more
wiley   +1 more source

Comparison of the Effects of Sevoflurane and Desflurane on Endothelial Glycocalyx in Patients Undergoing Laparoscopic Hysterectomy: A Randomized, Double-Blind Trial

open access: yesTurkish Journal of Anaesthesiology and Reanimation
Objective: Various enzymes, reactive oxygen species, inflammatory conditions, and major surgeries cause endothelial glycocalyx breakdown. Inhalation of anaesthetic agents may have protective effects on the endothelium.
Kemal Tolga Saraçoğlu   +8 more
doaj   +1 more source

Origin and deposition of basement membrane heparan sulfate proteoglycan in the developing intestine. [PDF]

open access: bronze, 1989
Patricia Simon‐Assmann   +3 more
openalex   +1 more source

Bioactive Polysulfate‐Based Nano‐Assemblies Against Virus Infection

open access: yesSmall, EarlyView.
Nano‐assemblies with a defined brush‐like corona are developed from sulfated polyglycerol to inhibit virus infection. The sulfate residues on the surface can actively bind the virus and entrap it from entering the host cells. This nanosystem is demonstrated potent inhibition against both HSV‐1 and SARs‐CoV‐2.
Guoxin Ma   +9 more
wiley   +1 more source

Heparan sulfate gets specific

open access: yesThe Journal of Cell Biology, 2001
Proteoglycans on the cell surface can exhibit a baffling diversity of structures, but the relative importance of that diversity in controlling the specificity of interactions between proteins is not known. On page 845, Allen et al. demonstrate that heparan sulfate serves as a tissue-specific regulator of interactions between FGF family members and FGF ...
openaire   +3 more sources

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