Results 111 to 120 of about 5,487 (200)

Discovery of new TeV supernova remnant shells in the Galactic plane with H.E.S.S

open access: yes, 2016
Supernova remnants (SNRs) are prime candidates for efficient particle acceleration up to the knee in the cosmic ray particle spectrum. In this work we present a new method for a systematic search for new TeV-emitting SNR shells in 2864 hours of H.E.S.S ...
Capasso, M.   +12 more
core   +3 more sources

An Overview of Hutchinson Gilford Progeria Syndrome (HGPS)

open access: yesBritish Journal of Medicine and Medical Research, 2015
Hutchinson Gilford Progeria Syndrome (HGPS) is a rare genetic disorder. The disorder is characterized by premature aging, generally leading to death. The purpose of this article is to review Hutchinson Gilford Progeria Syndrome and its characteristics.
Maria Tsiligiri   +3 more
openaire   +1 more source

Inhibition of JAK-STAT Signaling with Baricitinib Reduces Inflammation and Improves Cellular Homeostasis in Progeria Cells

open access: yesCells, 2019
Hutchinson-Gilford progeria syndrome (HGPS), a rare premature aging disorder that leads to death at an average age of 14.7 years due to myocardial infarction or stroke, is caused by mutations in the LMNA gene.
Chang Liu   +3 more
doaj   +1 more source

Potential Role of p53 in Huchinson-Gilford Progeria Syndrome [PDF]

open access: yes, 2017
Undergraduate ...
Eschedor, Danielle   +2 more
core  

iTRAQ-Based Analysis of Progerin Expression Reveals Mitochondrial Dysfunction, Reactive Oxygen Species Accumulation and Altered Proteostasis [PDF]

open access: yes, 2015
[Abstract] Introduction. Nuclear accumulation of a mutant form of the nuclear protein Lamin-A, called Progerin (PG) or Lamin AΔ50, occurs in Hutchinson-Gilford Progeria Syndrome (HGPS) or Progeria, an accelerated aging disease. One of the main symptoms
Arufe, M.C.   +10 more
core   +3 more sources

Heteroscedastic Gaussian processes for uncertainty modeling in large-scale crowdsourced traffic data

open access: yes, 2018
Accurately modeling traffic speeds is a fundamental part of efficient intelligent transportation systems. Nowadays, with the widespread deployment of GPS-enabled devices, it has become possible to crowdsource the collection of speed information to road ...
Pereira, Francisco C., Rodrigues, Filipe
core   +1 more source

Vascular cells derived from Hutchinson-Gilford progeria syndrome (HGPS) inducible pluripotent stem cells [PDF]

open access: yes, 2014
To study the vulnerability of smooth muscle cells (SMCs) in Hutchinson-Gilford Progeria Syndrome (HGPS)
Ferreira, Lino   +4 more
core  

Genome-wide redistribution of BRD4 binding sites in transformation resistant cells

open access: yesGenomics Data, 2015
Hutchinson–Gilford progeria syndrome (HGPS) patients do not develop cancer despite a significant accumulation of DNA damage in their cells. We have recently reported that HGPS cells are refractory to experimental oncogenic transformation and we ...
Han Si   +6 more
doaj   +1 more source

Hawaii Geothermal Project. Well completion report: HGP-A [PDF]

open access: yes, 1976
Procedures followed and equipment used in completion of the well to 6,455 feet are described. (MHR)
openaire   +2 more sources

MG132‐induced progerin clearance is mediated by autophagy activation and splicing regulation

open access: yesEMBO Molecular Medicine, 2017
Hutchinson–Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point mutation in LMNA encoding A‐type lamins.
Karim Harhouri   +7 more
doaj   +1 more source

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