Results 41 to 50 of about 5,487 (200)
Frontiers in Physiology, 2022 Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare genetic disorder that causes accelerated aging and a high risk of cardiovascular complications. However, the underlying mechanisms of cardiac complications of this syndrome are not fully understood ...
Gustavo Monnerat +17 more
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Effect of Magnesium on Replication of Rhinovirus HGP [PDF]
Journal of Virology, 1967 It is known that plaque formation by some rhinoviruses is greatly enhanced by increasing the concentration of MgCl 2 . The mechanism of this action was studied by investigating the effects of MgCl 2 on rhinovirus HGP adsorption, growth, clumping, thermal stability, and cell susceptibility to ...
M, Fiala, G E, Kenny
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From Cellular Characteristics to Disease Diagnosis: Uncovering Phenotypes with Supercells [PDF]
, 2013 Cell heterogeneity and the inherent complexity due to the interplay of multiple molecular processes within the cell pose difficult challenges for current single-cell biology.
Banavar, Jayanth R. +12 more
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HGPS-Derived iPSCs For The Ages [PDF]
Cell Stem Cell, 2011 In this issue of Cell Stem Cell, Zhang et al. (2011) generate patient-derived iPSCs for one of the major premature aging diseases, Hutchinson-Gilford Progeria Syndrome (HGPS). These cells are a much-needed new tool to study HGPS, and their use may lead to novel insights into mechanisms of aging.
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Biology Open, 2012 Summary Hutchinson-Gilford progeria syndrome (HGPS, OMIM 176670) is a rare disorder characterized by segmental accelerated aging and early death from coronary artery disease or stroke. Nearly 90% of HGPS sufferers carry a G608G mutation within exon 11 of
Vera Wenzel +7 more
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IEEE Access, 2023 Multi-vector smart local energy systems are playing an increasingly importantly role in the fast-track decarbonisation of our global energy services. An emergent contributor to global decarbonisation is green hydrogen. Green hydrogen can remove or reduce
Hani Gharavi Ahangar +2 more
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The Galactic sky through H.E.S.S. eyes
, 2015 The High Energy Stereoscopic System (H.E.S.S.) is an array of five imaging atmospheric Cherenkov telescopes. Since 2003 it has been operating in the configuration of four 12 m telescopes complemented in 2012 by a much bigger 28 m telescope in the centre ...
Sushch, I.
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Generation of a Hutchinson–Gilford progeria syndrome monkey model by base editing
Protein & Cell, 2020 Many human genetic diseases, including Hutchinson-Gilford progeria syndrome (HGPS), are caused by single point mutations. HGPS is a rare disorder that causes premature aging and is usually caused by a de novo point mutation in the LMNA gene. Base editors
Fang Wang +17 more
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Mouse models for understanding the molecular mechanism of bone disease in Hutchinson-Gilford progeria syndrome [PDF]
, 2011 Aging is a complex process affecting all people. Intense research is applied to elucidate the biological basis of aging and disease that develop with aging.
Schmidt, Eva
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Hutchinson-Gilford Progeria Syndrome (HGPS)
Journal of Oral Diagnosis, 2016 Hutchinson-Gilford Progeria Syndrome (HGPS) is an extremely rare genetic condition characterized by premature aging and it’s about one case for every four to eight million people. Children affected usually have premature death due to cardiovascular problems.
Alexandre Simoes Nogueira +6 more
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