Results 251 to 260 of about 19,695,084 (324)

The impact of subtotal pancreatectomy on people with congenital hyperinsulinism and their caregivers. [PDF]

Front Endocrinol (Lausanne)
Rohli KE, Banerjee I, Christesen HT, De Leon DD, Lopez LN, Raskin J, Pasquini TLS.   +6 more
europepmc   +1 more source

The genome sequence of a muscid fly, <i>Hydrotaea militaris</i> (Meigen, 1826) (Diptera: Muscidae). [PDF]

Wellcome Open Res
Falk S, Crowley LM, University of Oxford and Wytham Woods Genome Acquisition Lab, Darwin Tree of Life Barcoding Collective, Wellcome Sanger Institute Tree of Life Management, Samples and Laboratory team, Wellcome Sanger Institute Scientific Operations: Sequencing Operations, Wellcome Sanger Institute Tree of Life Core Informatics team, Tree of Life Core Informatics collective, Darwin Tree of Life Consortium.   +9 more
europepmc   +1 more source

Noncoding Variants in Intron 2 of HK1 Associated With Hyperinsulinism With Variable Clinical Phenotype.

J Clin Endocrinol Metab
Boodhansingh KE, Lord K, Sigal W, Benjet JE, Chen P, Juliana CA, Mitteer L, Bhatti T, Stanley CA, De Leon DD, Ganguly A.   +10 more
europepmc   +1 more source

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A comparison of the neuroprotective efficacy of individual oxime (HI-6) and combinations of oximes (HI-6+trimedoxime, HI-6+K203) in soman-poisoned rats

Drug and Chemical Toxicology, 2011
The ability of two combinations of oximes (HI-6+trimedoxime, HI-6+K203) to reduce soman-induced acute neurotoxic signs and symptoms was compared with the neuroprotective efficacy of the oxime HI-6 alone, using a functional observational battery. Soman-induced neurotoxicity and the neuroprotective effects of HI-6 alone and HI-6 combined with trimedoxime
Jiri, Kassa, Jana Zdarova, Karasova, Sandra, Tesarova   +2 more
openaire   +3 more sources

In vitro and in vivo genotoxicity assessment of HI-6 dimethanesulfonate/oxime

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2014
Organophosphate compounds, which induce organophosphate poisoning, were originally used as pesticides. But this type of product has also been used as warfare nerve agent like sarin, soman, Russian VX, or tabun. HI-6-dimethanesulfonate is a salt of the oxime HI-6 used in the treatment of nerve-agent poisoning.
Lauren, Nakab, Isabelle, Bardot, Sébastien, Bardot, Sophie, Simar, Daniel, Marzin, Fabrice, Nesslany   +5 more
openaire   +3 more sources

The pharmacokinetics of HI‐6 in beagle dogs

Biopharmaceutics & Drug Disposition, 1983
AbstractThe pharmacokinetics of HI‐6 were studied following intravenous administration to beagle dogs (n = 7). The bioavailability of two different strength intramuscularly administered doses was also determined in the same animals. After a 20 mg kg−1 intravenous dose, the mean (±S.D.) initial HI‐6 plasma concentration was 93·1 ± 10·μg ml−1.
K J, Simons, C J, Briggs
openaire   +3 more sources