Results 41 to 50 of about 6,653 (173)
Clinical and Translational Science, Volume 19, Issue 6, June 2026.ABSTRACT CYP2C19 genetic polymorphisms impact the antiplatelet effect of clopidogrel and associate with ischemic and bleeding risk in patients undergoing percutaneous coronary intervention (PCI). This study aimed to evaluate the association of CYP2C19 and platelet reactivity (PR) with these risks, in atrial fibrillation (AF) patients undergoing PCI ...
Diona Gjermeni +12 more
wiley +1 more source
Journal of Pharmacopuncture, 2004 Objective : This experimental studies were performed in order to prove the effect of Hirudin Herbal-acupuncture by using rats that had neuronal damage due to the Middle Cerebral Artery Occulsion(MCAO).
Suk Jae-Wook +4 more
doaj +1 more source
Diabetes and Delayed Wound Healing: Molecular Mechanisms and Dermatological Interventions
International Wound Journal, Volume 23, Issue 6, June 2026.ABSTRACT Diabetes mellitus is a global burden that affects wound healing at nearly every stage, transforming what should be a coordinated and self‐limited repair process into a chronic, non‐healing state. In diabetic patients, sustained hyperglycemia drives persistent inflammation, impaired angiogenesis, fibroblast dysfunction and extracellular matrix ...
Sasha Jreije +4 more
wiley +1 more source
Case Reports and Experts Opinions about Current Use of Leech Therapy in Dermatology and Cosmetology
Cosmetics, 2022 This article aimed to determine the experts’ opinion on the use of hirudotherapy in cosmetology, to supplement knowledge, and to identify factors that, in the opinion of experts, affect the effectiveness and frequency of use of this method in eliminating
Ewelina Ząbkowska +3 more
doaj +1 more source
Albumin Restores Endothelial Cell Mitochondrial Morphology in Patients With Decompensated Cirrhosis
Liver International, Volume 46, Issue 5, May 2026.ABSTRACT Background & Aims Endothelial cell (EC) activation is a critical driver of disease progression in cirrhosis, contributing to acute decompensation (AD) and acute‐on‐chronic liver failure (ACLF). Although human albumin administration improves EC function in cirrhotic patients with hypoalbuminemia, its direct effects on ECs remain unclear.
Susan E. Fischer +5 more
wiley +1 more source
Binding of hirudin to meizothrombin [PDF]
Protein Engineering Design and Selection, 1998 Prothrombin (coagulation factor II) is the inactive precursor molecule of thrombin (coagulation factor IIa). Proteolytic cleavage of the peptide bond Arg320-Ile321 converts prothrombin into the two-chain thrombin precursor meizothrombin. Meizothrombin hydrolyses peptidyl substrates, but cleavage of fibrinogen is poor.
B E, Fischer +3 more
openaire +2 more sources
Platelets, 2018 The Multiplate is a popular instrument that measures platelet function using whole blood. Potentially considered a point of care instrument, it is also used by hemostasis laboratories.
Kent Chapman, Emmanuel J. Favaloro
doaj +1 more source
Pathogen‐reduced plasma, cryoprecipitate reduced for therapeutic plasma exchange
Transfusion, Volume 66, Issue 4, Page 664-676, April 2026.Abstract Background Therapeutic plasma exchange (TPE) for thrombotic thrombocytopenic purpura (TTP) and auto‐immune disorders involves repeated patient exposure to allogenic plasma with the risk of transfusion‐transmitted infection (TTI).
Florian Tupin +6 more
wiley +1 more source
Small Structures, Volume 7, Issue 3, March 2026.Armed with unique structural and functional properties, elastin‐like polypeptides attract their attentions as programmable materials in biomedical applications, including fusion tags for protein and nucleic acid purification; nanocarriers for protein, chemotherapeutics, and imaging agent delivery; hydrogels for tissue regeneration, 3D model ...
Yang Yuan +9 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 2, February 2026.ABSTRACT Background and Aims Male infertility, often characterized by impaired sperm parameters, remains a significant clinical challenge. This study aimed to evaluate the efficacy and safety of hirudotherapy (medicinal leech therapy) in improving sperm quality parameters in men with idiopathic infertility.
Mozhde‐Sadat Abtahi‐Forooshani +3 more
wiley +1 more source