Results 71 to 80 of about 7,899 (213)
, 2013 Lane M, molecular mass standards (116 to 14.4 kDa ). a. Loading was 10 µL of culture supernatant of unlabeled RGD-hirudin for 0 to 20 h after methanol induction. b.
Min Yu (120607) +8 more
core +1 more source
A COMPARISON OF HIRUDIN WITH HEPARIN IN THE PREVENTION OF RESTENOSIS AFTER CORONARY ANGIOPLASTY [PDF]
, 1995 Background. The likelihood of restenosis is a major limitation of coronary angioplasty. We studied whether hirudin, a highly selective inhibitor of thrombin with irreversible effects, would prevent restenosis after angioplasty.
SIMON, R +11 more
core +3 more sources
Anticoagulant efficacy of PEG-Hirudin in patients on maintenance hemodialysis
, 2004 Anticoagulant efficacy of PEG-Hirudin in patients on maintenance hemodialysis.BackgroundHeparins are currently the anticoagulants of choice in long-term hemodialysis (HD).
Ulbricht, Kristina +6 more
core +1 more source
Isolation and purification of hirudin from a blood-sucking leech, Hirudo nipponia, in China
, 1997 This paper deals with the isolation and purification of hirudin from a bloodsucking leech, Hirudo nipponia in China. Essentially, the experimental process requires an anion exchange chromatography on DEAE-C-52 and a gel filtration chromatography on ...
Yin Ping +2 more
core
New Advances in Biologic Treatment for Malignant Atrophic Papulosis: A Systematic Review
Dermatologic Therapy, Volume 2026, Issue 1, 2026.Background Malignant atrophic papulosis (MAP) is the systemic subtype of Degos disease, characterized by high lethality. Currently there is no standardized treatment protocol. Steroids and immunosuppressive therapies result in limited effectiveness. Biologic treatments offer promising therapeutic potential for MAP and significantly improve prognosis ...
Jia-Wei Liu +3 more
wiley +1 more source
Ecarin clotting time but not aPTT correlates with PEG-hirudin plasma activity
, 2001 Background: Novel antithrombotic agents such as hirudin have shown promise in the therapy of acute coronary syndromes. PEG-hirudin (polyethyleneglycol conjugated hirudin) has been developed to provide a longer plasma half-life and more stable ...
Nordt, T. +8 more
core +1 more source
Veterinary Medicine International, Volume 2026, Issue 1, 2026.The livestock industry in Ethiopia suffers greatly from parasites and parasitic diseases including leech infestation. Leech infestation is a serious disease of animals and occasionally humans, but it is usually ignored. A cross‐sectional study design was carried out from January 2022 to June 2022 to estimate the prevalence of leech infestation in ...
Moges Maru +11 more
wiley +1 more source
Positional effects of sulfation in hirudin and hirudin PA related anticoagulant peptides
, 2009 [[abstract]]C-Terminal fragment analogues of the leech protein hirudin or the related protein hirudin PA block thrombin's cleavage of fibrinogen. Three series of synthetic peptides were synthesized to study the effects of sulfation in hirudin-derived ...
Payne MH; Krstenansky JL; Yates MT; Mao SJT
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Comparison of hirudin and hirudin PA C-terminal fragments and related analogs as antithrombin agents
, 2009 [[abstract]]Hirudin PA54-66 and related hirudin fragment analogs were synthesized and assessed for their inhibition of thrombin-induced fibrin-clot formation in plasma.
Krstenansky JL;Owen TJ;Yates MT;Mao SJT
core
Effects of medium composition on hirudin production in recombinant Saccharomyces cerevisiae
, 1996 The enriched medium based on yeast nitrogen base(YNB)increased hirudin synthesis and secretion in rccombinant Saccharomyces cerevisiae in batch and fed-batch cultures.
Myoung-Dong Kim +3 more
core +1 more source