Results 221 to 230 of about 391,128 (337)

The nBAF complex subunit CREST/SS18L1 regulates hippocampal memory processes via tyrosine 397 and histone acetyltransferase CBP. [PDF]

Cell Rep
Garcia FG, Farias de Albuquerque M, Johnson V, Kramár E, Changizi K, Abdelkarim S, Augustynski AS, Matheos DP, Picone J, Fetterly TL, Rodriguez A, Childs J, Gomez-Arboledas A, Winter J, Heller E, Baldi P, Wood MA.   +16 more
europepmc   +1 more source

Genomic profiling of Mexican patients with B‐cell precursor acute lymphoblastic leukemia reveals clinically significant somatic and potential germline variants

The Journal of Pathology: Clinical Research, Volume 12, Issue 5, September 2026.
Abstract B‐cell precursor acute lymphoblastic leukemia (preB‐ALL) is characterized by pathogenic variants currently used in precision oncology. However, the mutational landscape of Mexican children with preB‐ALL has not yet been thoroughly explored and defined in terms of the clinical significance.
Daniel Martínez Anaya, María del Rocío Juárez‐Velázquez, Ulises Juárez Figueroa, Michael Dean, Consuelo Salas Labadía, Marian Valladares Coyotecatl, Adriana Reyes León, Norma López Santiago, Luis Juárez Villegas, Marta Zapata Tarrés, Patricia Pérez‐Vera   +10 more
wiley   +1 more source

Histone acetyltransferase 1 promotes ovarian cancer progression by regulating cell proliferation and the cell cycle. [PDF]

Oncol Lett
Han X, Liu L, Li J, Zhi Y, Zhao L, Yuan L, Ouyang X, Liu J.   +7 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, Volume 7, Issue 3, Page 109-124, September 2026.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Expression of Concern: Histone acetyltransferase inhibition reverses opacity in rat galactose-induced cataract. [PDF]

PLoS One
PLOS One Editors.
europepmc   +1 more source

Histone acetyltransferase PCAF regulates inflammatory molecules in the development of renal injury

Epigenetics, 2015
Jin Huang, D. Wan, Jian-Shuang Li, Hong Chen, Kun Huang, Ling Zheng   +5 more
semanticscholar   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, Volume 13, Issue 50, 7 September 2026.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Enhancement of <i>Monascus</i> Azaphilone Pigments Production Without Citrinin Contamination by Targeting Overexpression of Histone Acetyltransferase MrEsa1 and Deletion of Polyketide Synthase PksCT. [PDF]

J Fungi (Basel)
Zhang J, Yang S, Wang Q, Liu Q, Chen J, Gong Y, Xu R, Shao Y.   +7 more
europepmc   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, Volume 13, Issue 54, 28 September 2026.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

GCN5-related histone acetyltransferase HOOKLESS2 regulates fungal resistance and growth in tomato. [PDF]

New Phytol
Jaiswal N, Liao CJ, Hewavidana AI, Mengiste T.   +3 more
europepmc   +1 more source