Results 231 to 240 of about 73,046 (329)

Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor α

, 2017
Masayoshi Iizuka, Takao Susa, Mimi Tamamori‐Adachi, Hiroko Okinaga, Tomoki Okazaki   +4 more
openalex   +2 more sources

Long‐Term Stress Adaptation as a Highly‐Conserved Key Factor in Yeast Aging

Aging Cell, Volume 25, Issue 5, May 2026.
This study shows that long‐term, but not short‐term, stress exposure triggers molecular changes in yeast that mirror established hallmarks of aging, including altered proteostasis, epigenetic shifts, and reduced lifespan. These changes are reversible upon stress removal, and the genes involved are conserved across all domains of life. ABSTRACT Aging is
Yanzhuo Kong, Damola Adejoro, Christopher Winefield, Stephen L. W. On, Philip A. Wescombe, Arvind Subbaraj, Andrew Saunders, Venkata Chelikani   +7 more
wiley   +1 more source

GCN5-related histone acetyltransferase HOOKLESS2 regulates fungal resistance and growth in tomato. [PDF]

New Phytol
Jaiswal N, Liao CJ, Hewavidana AI, Mengiste T.   +3 more
europepmc   +1 more source

Structure and flexibility of the yeast NuA4 histone acetyltransferase complex. [PDF]

Elife, 2022
Zukin SA, Marunde MR, Popova IK, Soczek KM, Nogales E, Patel AB.   +5 more
europepmc   +1 more source

Multi‐Omics Signatures of Organ Clocks in Biological Aging and Disease: A Conceptual Framework for Organ‐Specific Aging Clocks

Aging Cell, Volume 25, Issue 5, May 2026.
Organ‐specific aging clocks integrating genomics, epigenomics, transcriptomics, proteomics, and metabolomics offer a more accurate assessment of biological aging than single‐omics approaches. This review proposes a multi‐omics framework emphasizing tissue data, longitudinal study designs, and clinically meaningful training outcomes to advance the ...
Maria Vasileiou, Gabor Liposits, Bara Barakat, Nam P. Nguyen   +3 more
wiley   +1 more source

Growth phase diets diminish histone acetyltransferase Gcn5 function and shorten lifespan of Drosophila males. [PDF]

EMBO Rep
Mizutani S, Furuya K, Mure A, Takahashi Y, Mori A, Sakurai N, Suito T, Nagao K, Umeda M, Watanabe K, Hattori Y, Uemura T.   +11 more
europepmc   +1 more source

Emerging Role of Ferroptosis in Diabetes and Associated Complications: When Metabolic Dysregulation Meets Cell Death

Cell Proliferation, Volume 59, Issue 5, May 2026.
This study identifies ferroptosis as a key driver of diabetes and its complications via iron metabolism and lipid peroxidation, elucidates organelle interactions underlying cell vulnerability, and provides insights for targeted therapies against metabolic disorders.
Zheng Wang, Ying Zhang, Yue Xu, Mengyuan Yang, Yuan Wei, Yuan Li, Tongyue Yang, Xu Wang, Chaona Yang, Qi Feng, Guolan Xing   +10 more
wiley   +1 more source

<i>Arabidopsis</i> HOOKLESS1 acts as a histone acetyltransferase to promote cotyledon greening during seedling de-etiolation. [PDF]

Proc Natl Acad Sci U S A
Peng Y, Peng T, Chu Y, Yan W, Yao R, Wen X, Qiu Y, Wang M, Xiao Z, Zhang D, Chen X, Yin Z, Wang Y, Guo H.   +13 more
europepmc   +1 more source

Regulation of the Growth‐Inhibitory Activity of Fhl1 via Interaction With Ifh1 and Crf1 at the Ribosomal Protein Gene Promoters in Saccharomyces cerevisiae

Genes to Cells, Volume 31, Issue 3, May 2026.
Under nutrient‐rich conditions, Ifh1 recruited to the RPG promoters by the FHA domain of Fhl1 promotes growth while masking the latent inhibitory activity of Fhl1. Upon starvation or stress, dissociation of Ifh1 exposes this inhibitory activity, restricting RPG transcription and cell proliferation, whereas Crf1 functions to mitigate excessive ...
Naoki Shimamura, Koji Kasahara
wiley   +1 more source

Lily Transcription Factors LlPLATZ1 and LlMYB4 Orchestrate the Homeostasis of Heat Stress Responses via Antagonistic Regulation of LlHSF24

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3407-3425, May 2026.
ABSTRACT Heat stress significantly damages crop yield and quality. PLATZ (PLANT A/T‐RICH SEQUENCE‐AND ZINC‐BINDING PROTEIN) transcription factors play pivotal roles in plant growth, development, and environmental stress responses. While the functions of PLATZ members in response to drought and salt stress are well characterised, their roles in heat ...
Xue Gong, Jun Xiang, Ziwei Liao, Tian Zhang, Liping Ding, Qianqian Fang, Nianjun Teng, Ze Wu   +7 more
wiley   +1 more source