Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity. [PDF]
Chakraborty R +14 more
europepmc +1 more source
Liquid–Liquid Phase Separation in Major Hallmarks of Cancer
Aberrant condensates formed through phase separation are involved in the dysregulation of various critical cellular processes, including genome stability, transcriptional regulation and signal transduction, thereby promoting malignant transformation and the acquisition of multiple cancer hallmarks.
Chen‐chen Xie +10 more
wiley +1 more source
The HAC1 Histone Acetyltransferase Promotes Leaf Senescence via Regulation of ERF022 [PDF]
Will E. Hinckley +3 more
openalex +1 more source
The Transcriptional Coactivators p300 and CBP Are Histone Acetyltransferases
V. Ogryzko +4 more
semanticscholar +1 more source
A novel assay evaluates plant biostimulants targeting the brassinosteroid receptor BRI1, a central component in plant growth and development. By expressing BRI1 in fission yeast, functional activation by brassinolide (BL) was enabled. Transcriptomic profiling identified BL‐responsive genes, leading to a GFP‐based reporter system. This platform offers a
Maribel Marquina +9 more
wiley +1 more source
Discovery of spirohydantoins as selective, orally bioavailable inhibitors of p300/CBP histone acetyltransferases. [PDF]
Ji Z +17 more
europepmc +1 more source
A pair of transposon-derived proteins function in a histone acetyltransferase complex for active DNA demethylation [PDF]
Cheng‐Guo Duan +17 more
openalex +1 more source
Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila
The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause +5 more
wiley +1 more source
Histone Acetyltransferases in Smooth Muscle Cell Phenotype Switching: Redundant No Longer. [PDF]
Jaffe IZ.
europepmc +1 more source
Melatonin and the Dental Pulp: A Scoping Review
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer +2 more
wiley +1 more source

