Results 201 to 210 of about 223,415 (361)
The vitamin D receptor (VDR) regulates hair follicle biology through ligand‐dependent and ligand‐independent mechanisms by heterodimerizing with retinoid X receptor, recruiting coactivator complexes, and activating target genes including Wnt inhibitors, hair keratins, and cell cycle regulators.
Liancheng Guan +8 more
wiley +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Identification of a Human Histone Acetyltransferase Related to Monocytic Leukemia Zinc Finger Protein [PDF]
Nathalie Champagne +7 more
openalex +1 more source
Histone Acetyltransferase Inhibitors: Where Art Thou? [PDF]
Jonathan B, Baell, Wenjun, Miao
openaire +2 more sources
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
BRCA2 cooperates with histone acetyltransferases in androgen receptor-mediated transcription
Sook Shin, Inder M. Verma
openalex +1 more source
HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression [PDF]
Manti Guha +15 more
openalex +1 more source

