Results 231 to 240 of about 35,141 (364)

Interaction of TFAP2A with the Ku70/80 complex is crucial for HIF‐dependent activation of hypoxia‐inducible genes

open access: yesThe FEBS Journal, EarlyView.
Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura   +8 more
wiley   +1 more source

Overlapping roles for the histone acetyltransferase activities of SAGA and Elongator in vivo

open access: green, 2000
Birgitte Ø. Wittschieben   +4 more
openalex   +2 more sources

Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity

open access: yesThe FEBS Journal, EarlyView.
RANKL treatment induces expression of the aconitate decarboxylase (ACOD1) in differentiating osteoclasts, which increases succinate levels. The initially high expression of ACOD1 decreases towards the end of differentiation when the levels of the desuccinylase SIRT5 increase. Succinylation of citrate synthase (CS) was detected exclusively in stimulated
Dayoung Yu   +7 more
wiley   +1 more source

Acetylation of p53 Activates Transcription through Recruitment of Coactivators/Histone Acetyltransferases [PDF]

open access: bronze, 2001
Nickolai A. Barlev   +6 more
openalex   +1 more source

How Histone Acetyltransferases Shape Plant Photomorphogenesis and UV Response. [PDF]

open access: yesInt J Mol Sci
Boycheva I   +4 more
europepmc   +1 more source

Notch dependent chromatin remodeling enables Gata3 binding and drives lineage specific CD8+ T cell function

open access: yesImmunology &Cell Biology, Volume 103, Issue 4, Page 365-382, April 2025.
This study examines how Notch signaling conditions the genome landscape within activated CD8+ T cells in such a way to alter the binding pattern of transcription factors such as Gata3. This Notch dependent conditioning directs Gata3 binding to CD8+ T cell lineage specific gene loci enabling generation of effective T cell responses.
Jessie O'Hara   +11 more
wiley   +1 more source

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