Influenza A virus nucleoprotein is acetylated by histone acetyltransferases PCAF and GCN5. [PDF]
Hatakeyama D +14 more
europepmc +1 more source
NF-Y Is Associated with the Histone Acetyltransferases GCN5 and P/CAF [PDF]
A Currie
openalex +1 more source
Prenatal dexamethasone exposure (PDE) persistently upregulates hepatic CYP3A1/CYP2B1 in offspring via glucocorticoid receptor (GR) activation. In vivo and in vitro studies show GR promotes P300/CBP binding to the constitutive androstane receptor (CAR) promoter, sustaining histone acetylation (H3K9/K27ac) and enhancing CYP expression. The GR–CAR pathway
Xiaoxiang Sun +9 more
wiley +1 more source
Intrinsic ubiquitin E3 ligase activity of histone acetyltransferase Hbo1 for estrogen receptor α
Masayoshi Iizuka +4 more
openalex +2 more sources
Metabolism‐Regulating Nanomedicines for Cancer Therapy
This review highlights metabolism‐regulating nanomedicines designed to target glycolytic, lipid, amino acid, and nucleotide pathways in tumors. By incorporating metabolism‐regulating agents into versatile nanocarriers such as liposomes, micelles, dendrimers, and engineered bacteria, these platforms achieve targeted delivery, controlled release ...
Xiao Wu, Shiyi Geng, Jian Yang
wiley +1 more source
Caffeic Acid Phenethyl Ester Inhibits UV-Induced MMP-1 Expression by Targeting Histone Acetyltransferases in Human Skin. [PDF]
Shin EJ +5 more
europepmc +1 more source
License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication
Origin licensing constitutes the first step in initiating eukaryotic genome replication. Licensed origins are marked by an MCM double hexamer complex. This article reviews the molecular mechanisms of MCM double hexamer loading in yeast and higher eukaryotes, based on insights gained from biochemical reconstitution and structural analyses.
Victoria Frisbie, Franziska Bleichert
wiley +1 more source
Epigenetic Alterations Induced by Photothrombotic Stroke in the Rat Cerebral Cortex: Deacetylation of Histone h3, Upregulation of Histone Deacetylases and Histone Acetyltransferases. [PDF]
Demyanenko S, Uzdensky A.
europepmc +1 more source
Pioneer Factor FOXA1 Boosts CHO Cell Productivity
Graphical Abstract and Lay Summary FOXA1 binds directly to the EF1α and CMV promoters that are widely used to drive transgene expression. It stimulates transcription by recruiting cofactors that manipulate the epigenetic environment, including TET1 that demethylates DNA, p300 that acetylates histones and SWI/SNF that remodels nucleosomes.
Sienna P. Butterfield +2 more
wiley +1 more source
Diversity, evolution and expression profiles of histone acetyltransferases and deacetylases in oomycetes. [PDF]
Wang XW, Guo LY, Han M, Shan K.
europepmc +1 more source

