Results 41 to 50 of about 241,476 (303)
The Sas3p and Gcn5p histone acetyltransferases are recruited to similar genes. [PDF]
, 2007 Background Specific histone modifications can perform several cellular functions, for example, as signals to recruit trans-acting factors and as modulators of chromatin structure.
Lorena E Rosaleny +10 more
core +1 more source
Antiviral Research, 2017 The hepatitis B core protein (HBc) has been suggested to interact with covalently closed circular DNA (cccDNA) and regulate hepatitis B virus (HBV) transcription. However, direct evidence is lacking.
Chun-kong Chong +8 more
semanticscholar +1 more source
Hepatology, EarlyView., 2022 KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou +15 more
wiley +1 more source
How do histone acetyltransferases select lysine residues in core histones? [PDF]
, 1998 Acetylation of specific lysines of core histone N-terminal tails correlates with chromatin assembly and specific regulation of gene expression. Core histones acetylated at particular lysines mediate effects on chromatin function; however, the manner in ...
Kimura, Akatsuki +3 more
core +1 more source
Plant Responses to Abiotic Stress Regulated by Histone Deacetylases
Frontiers in Plant Science, 2017 In eukaryotic cells, histone acetylation and deacetylation play an important role in the regulation of gene expression. Histone acetylation levels are modulated by histone acetyltransferases and histone deacetylases (HDACs).
Ming Luo +5 more
doaj +1 more source
Histone Acetylation and Modifiers in Renal Fibrosis
Frontiers in Pharmacology, 2022 Histones are the most abundant proteins bound to DNA in eukaryotic cells and frequently subjected to post-modifications such as acetylation, methylation, phosphorylation and ubiquitination.
Fengchen Shen +2 more
doaj +1 more source
ACL and HAT1 form a nuclear module to acetylate histone H4K5 and promote cell proliferation
Nature Communications, 2023 Acetyl-CoA utilized by histone acetyltransferases (HAT) for chromatin modification is mainly generated by ATP-citrate lyase (ACL) from glucose sources. How ACL locally establishes acetyl-CoA production for histone acetylation remains unclear.
Qiutao Xu +7 more
doaj +1 more source
Temporal and spatial distribution of histone acetylation in mouse molar development [PDF]
PeerJHistone acetylation is one of the most widely studied histone modification, regulating a variety of biological activities like organ development and tumorigenesis. However, the role of histone acetylation in tooth development is poorly understood.
Wen Du +4 more
doaj +2 more sources
Roles and regulation of histone acetylation in hepatocellular carcinoma
Frontiers in Genetics, 2022 Hepatocellular Carcinoma (HCC) is the most frequent malignant tumor of the liver, but its prognosis is poor. Histone acetylation is an important epigenetic regulatory mode that modulates chromatin structure and transcriptional status to control gene ...
Jin-kun Xia +8 more
doaj +1 more source
Genes & cancer, 2015 The development of B and T cells from hematopoietic precursors and the regulation of the functions of these immune cells are complex processes that involve highly regulated signaling pathways and transcriptional control.
Leila Haery +2 more
semanticscholar +1 more source