Results 171 to 180 of about 31,898 (266)
Myosin Post‐Translational Modifications Associated With Critical Illness Myopathy
ABSTRACT Background Critical illness myopathy is a common and devastating consequence of critical care, causing dramatic loss of muscle mass and function in intensive care unit patients. Functional deficits often exceed the loss in muscle mass and myosin content.
Fernando Ribeiro +9 more
wiley +1 more source
Decoding GUN1 in plastid‐to‐nucleus signaling: what it doesn't, what it does, and why it matters
Publication history of plant GUN1 research. Summary Plastid‐to‐nucleus retrograde signaling coordinates nuclear gene expression with the developmental and physiological state of plastids. GENOMES UNCOUPLED 1 (GUN1), a chloroplast‐localized PPR‐SMR protein, remains a central yet poorly understood component of this network.
Marco Wendler +2 more
wiley +1 more source
Structure of the human ATAD2 AAA+ histone chaperone reveals mechanism of regulation and inter-subunit communication. [PDF]
Cho C +4 more
europepmc +1 more source
Abstract Although seed represents an important means of plant pathogen dispersion, the seed–pathogen dialogue remains largely unexplored. A multiomic approach was performed at different seed developmental stages of common bean (Phaseolus vulgaris L.) during asymptomatic colonization by Xanthomonas citri pv.
Armelle Darrasse +6 more
wiley +1 more source
Polycomb (Pc), a core component of Polycomb Repressive Complex 1 (PRC1), is largely intrinsically disordered yet forms buffer‐ and concentration‐dependent higher‐order assemblies. Integrative biophysical analysis and cryo‐electron microscopy reveal dynamic, heterogeneous oligomers, whereas AlphaFold modeling suggests that structural organization is ...
Maria Zahid +4 more
wiley +1 more source
Structural basis for HIV-1 Rev recognition by the histone chaperone human Nap1. [PDF]
Eren E +3 more
europepmc +1 more source
Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features
ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato +6 more
wiley +1 more source
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Chromatin assembly by the histone chaperone HIRA facilitates Human Papillomavirus replication. [PDF]
Della Fera AN, Chen D, McBride AA.
europepmc +1 more source

