DAXX-dependent H3.3 deposition maintains myoblast cell identity independently of other histone chaperone complexes. [PDF]
Zoglio V +4 more
europepmc +1 more source
The histone chaperone FACT: a guardian of chromatin structure integrity. [PDF]
Jeronimo C, Robert F.
europepmc +1 more source
The linker histone chaperone Prothymosin α (PTMA) is essential for efficient DNA damage repair and the recruitment of PARP1. [PDF]
McKnight CA +3 more
europepmc +1 more source
Genome‐Wide In Silico Analysis of the Type VI Secretion System (T6SS) Within the Morganella Genus
▪ Species‐specific T6SS patterns among Morganella genus (M. morganii and M. sibonii). ▪ Only one‐third of M. morganii isolates haboured a T6SS. ▪ All M. sibonii possess four T6SS clusters. ▪ M. sibonii exhibited a wide diversity of effectors compared to M. morganii.
Mathilde Duque +4 more
wiley +1 more source
Histone chaperone-mediated co-expression assembly of tetrasomes and nucleosomes. [PDF]
Okimune KI +6 more
europepmc +1 more source
Shotgun metagenomic sequencing was used to characterize the functional potential of the Allium ampeloprasum rhizosphere microbiome under chemical fertilizer (G1), biofertilizer (G2), and unfertilized (Bulk) soil (G3) management practices. This study revealed that different fertilization regimes altered microbial functional profiles.
Oluwaseun Emmanuel Shittu +2 more
wiley +1 more source
The histone chaperone Spn1 preserves chromatin protections at promoters and nucleosome positioning in open reading frames. [PDF]
Tonsager AJ +5 more
europepmc +1 more source
Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang +12 more
wiley +1 more source
Histone chaperone HIRA complex regulates retrotransposons in embryonic stem cells. [PDF]
Zhang M +6 more
europepmc +1 more source
Encephalopathy: Cause, Pathogenesis, and Treatment
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv +7 more
wiley +1 more source

