Results 201 to 210 of about 31,898 (266)

The histone chaperone CAF-1 prevents homologous recombination-mediated instability of the budding yeast ribosomal DNA during replication-coupled DNA double-strand break repair. [PDF]

Nucleic Acids Res
Futami H, Yamaji T, Katayama Y, Arata N, Nagura M, Kobayashi T, Sasaki MM.   +6 more
europepmc   +1 more source

Histone chaperone NUCLEOSOME ASSEMBLY PROTEIN 1 proteins affect plant growth under nitrogen deficient conditions in Arabidopsis thaliana. [PDF]

Plant Biotechnol (Tokyo), 2023
Jie L, Sanagi M, Luo Y, Maeda H, Fukao Y, Chiba Y, Yanagisawa S, Yamaguchi J, Takagi J, Sato T.   +9 more
europepmc   +1 more source

Stearoyl‐CoA Desaturase‐1 Drives Tumor Growth by Interacting With Histone Deacetylase‐2 and Deacetylating Nucleophosmin‐1

MedComm, Volume 7, Issue 6, June 2026.
Hypoxia induces SCD1 and PLIN2 to drive lipid droplet‐dependent metabolic adaptation in cancer cells. PLIN2 supports survival under stress, whereas SCD1 promotes proliferation upon reoxygenation and remodels the acetylome via HDAC2‐mediated NPM1 deacetylation and destabilization.
Coline Wery, Laetitia Montero‐Ruiz, Eric Bonneil, Mohammad Farran, Robin Jehay, Quentin Herrara Garfia, Gregory Fettweis, Silvia Blacher, Charles Pottier, Gael Cobraiville, Yasmine Boumahd, Olivier Peulen, Agnès Noël, Franck Dequiedt, Marianne Fillet, Nor Eddine Sounni   +15 more
wiley   +1 more source

Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. [PDF]

Aging Cell
Jaber-Hijazi F, Arnold R, Swaminathan K, Gilroy K, Wenzel AT, Lagnado A, Kirschner K, Robertson N, Reid C, Fullarton N, Pawlikowski J, Rai TS, Baranyk I, Shi CH, Yip KY, Blyth K, Mesirov JP, Harris ML, Passos JF, Machesky LM, Adams PD.   +20 more
europepmc   +1 more source

Antisense-mediated repression of SAGA-dependent genes involves the HIR histone chaperone. [PDF]

Nucleic Acids Res, 2022
Soudet J, Beyrouthy N, Pastucha AM, Maffioletti A, Menéndez D, Bakir Z, Stutz F.   +6 more
europepmc   +1 more source

Conditional Modeling of GNAO1 Disorder Dissociates Circuit Specific Contributions to Pathology and Rationalizes Ameliorative Strategies

Movement Disorders, Volume 41, Issue 6, Page 1528-1541, June 2026.
Abstract Background Neurodevelopmental disorders feature various symptoms that frequently include seizures and motor manifestations, but their attribution to disruptions of specific circuits and molecular alterations is notoriously hard to establish, which limits therapeutic interventions.
Gloria Brunori, Stefano Zucca, Colten K. Lankford, Yi‐Zhi Wang, Marianna Franco, Nina A. Alekseeva, Sevinj Ahmedova, Han My Van, Jeffrey N. Savas, Kirill A. Martemyanov   +9 more
wiley   +1 more source

Phosphorylation of cytochrome c at tyrosine 48 finely regulates its binding to the histone chaperone SET/TAF-Iβ in the nucleus. [PDF]

Protein Sci
Tamargo-Azpilicueta J, Casado-Combreras MÁ, Giner-Arroyo RL, Velázquez-Campoy A, Márquez I, Olloqui-Sariego JL, De la Rosa MA, Diaz-Moreno I.   +7 more
europepmc   +1 more source

Molecular Insights into Noncanonical Histone Chaperone Complexes

Two fundamental macromolecular complexes required for the survival of eukaryotic cells are nucleosomes, which organize our genetic material (DNA), and ribosomes, which translate the information encoded by genes into functional proteins.
Sedor, Samantha
core  

Peroxisomal Lipid Metabolism as a Therapeutic Target in Leukemia

Molecular Nutrition &Food Research, Volume 70, Issue 11, 15 June 2026.
Peroxisomes are emerging as key regulators of lipid metabolism in leukemia. Enhanced metabolism of very‐long‐chain fatty acids (VLCFAs) supports leukemia cell survival, redox homeostasis, and therapeutic resistance. Pharmacologic disruption of peroxisomal fatty acid oxidation causes VLCFA accumulation, oxidative stress, and mitochondrial dysfunction ...
Ekaterina N. Parfenova, Paul A. Spagnuolo   +1 more
wiley   +1 more source

Histone Chaperone Deficiency in Arabidopsis Plants Triggers Adaptive Epigenetic Changes in Histone Variants and Modifications. [PDF]

Mol Cell Proteomics
Franek M, Nešpor Dadejová M, Pírek P, Kryštofová K, Dobisová T, Zdráhal Z, Dvořáčková M, Lochmanová G.   +7 more
europepmc   +1 more source