Results 171 to 180 of about 4,008 (211)

Histone lactylation: A key epigenetic modulator in the pathogenesis of metabolic dysfunction-associated steatohepatitis and alcoholic steatohepatitis. [PDF]

World J Hepatol
Singh MM, Shah A, Rajak S, Chaturvedi CP, Sinha RA.   +4 more
europepmc   +1 more source

Delactylase effects of SIRT3 on a positive feedback loop involving the RUNX1-glycolysis-histone lactylation in diabetic kidney disease. [PDF]

Int J Biol Sci
Shen S, Ying C, Fu X, Zeng X, Guo X, Wu H, Zhang L, Xu L.   +7 more
europepmc   +1 more source

Histone Lactylation-Mediated Metabolic Remodeling in Vascular Smooth Muscle Cells Aggravates Aortic Aneurysm and Dissection by Promoting Lactate Accumulation. [PDF]

Circulation
Liu L, Zhang J, Dong Z, Cui Y, Zou X, Lai H, Gu J, Weng X, Jin X, Qiu T, Pei Z, Hong W, Huang Y, Luo W, Pan L, Sun X, Zhang B, Shalamu A, Sun A, Ge J.   +19 more
europepmc   +1 more source

Cyclin B2 facilitates glycolysis and tumor progression in pancreatic ductal adenocarcinoma by promoting histone lactylation. [PDF]

BMC Cancer
Ma B, Li X, Ma Z, Yin Z, Gao L, Wang Y, Shi J, Liu X, Chen H.   +8 more
europepmc   +1 more source

Histone lactylation-mediated up-regulation of IGF2BP2 enhances ferroptosis resistance via Nrf2 in colorectal cancer. [PDF]

Clin Transl Med
Zhu JF, Guo DP, Lv HN, Liang ZY, Song J, Zeng W.   +5 more
europepmc   +1 more source

AKR1B10 reprograms neutrophils by histone lactylation to foster immune evasion in KRAS^G12C mutation colorectal cancer liver metastasis. [PDF]

J Exp Clin Cancer Res
Li W, Yuan W, Du Z, Wang X, Wang D, Xing S, Shen T, Lu C, Chen J, Yu A, Jiang X, Zhang S, Zheng S, Feng X, Wang T, Zuo J, Chen J, Zhang C, Wang X, Zhang C.   +19 more
europepmc   +1 more source

Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome. [PDF]

Signal Transduct Target Ther
Yu C, Liu T, Wang Y, Guo X, Chen Y, Zhao Y, Liu X, Huang W, Zhao S, Mo J, Hu H, Lv P, Wang X, Yang Z, Pan J, Ding G, Sheng J, Liu X, Yang H, Huang HF.   +19 more
europepmc   +1 more source

Histone lactylation: A new frontier in laryngeal cancer research (Review). [PDF]

Oncol Lett
Tong Q, Huang C, Tong Q, Zhang Z.
europepmc   +1 more source

Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells. [PDF]

Adv Sci (Weinh)
Li J, Tang C, Zhang X, Xing R, Guo Q.
europepmc   +1 more source

Histone lactylation-driven feedback loop modulates cholesterol-linked immunosuppression in pancreatic cancer. [PDF]

Gut
Yang J, Yu X, Xiao M, Xu H, Tan Z, Lei Y, Guo Y, Wang W, Xu J, Shi S, Yu X.   +10 more
europepmc   +1 more source