Results 161 to 170 of about 4,358 (213)

Emerging role of histone and non-histone lactylation in metabolic reprogramming of female-specific malignancies. [PDF]

World J Surg Oncol
Sun C, Hu D, Peng W, Cui Z, Lin Y.
europepmc   +1 more source

Investigating the Mechanistic Link Between Lactate-Induced Histone Lactylation and Cellular Senescence in Osteoarthritis Chondrocytes: Implications for Therapy. [PDF]

Int J Biol Sci
Zuo R, Wu C, Lin Z, Kong L, Wang F, Zhang X, Wei J, Lin Y, Yang E, Kang Q, Zhao S, Guan J, Zhao J.   +12 more
europepmc   +1 more source

Histone lactylation: A key epigenetic modulator in the pathogenesis of metabolic dysfunction-associated steatohepatitis and alcoholic steatohepatitis. [PDF]

World J Hepatol
Singh MM, Shah A, Rajak S, Chaturvedi CP, Sinha RA.   +4 more
europepmc   +1 more source

Histone lactylation leads to perioperative neurocognitive disorders by promoting the expression of Ralbp1 and inducing excessive mitochondrial fission in hippocampal neurons. [PDF]

Cell Mol Life Sci
Meng F, Cao S, Wu W, Zhang M, Jing Q, Xie Z, Sun X, Song J, Fei M, Chen Q, Gao X, Li C.   +11 more
europepmc   +1 more source

Delactylase effects of SIRT3 on a positive feedback loop involving the RUNX1-glycolysis-histone lactylation in diabetic kidney disease. [PDF]

Int J Biol Sci
Shen S, Ying C, Fu X, Zeng X, Guo X, Wu H, Zhang L, Xu L.   +7 more
europepmc   +1 more source

Cyclin B2 facilitates glycolysis and tumor progression in pancreatic ductal adenocarcinoma by promoting histone lactylation. [PDF]

BMC Cancer
Ma B, Li X, Ma Z, Yin Z, Gao L, Wang Y, Shi J, Liu X, Chen H.   +8 more
europepmc   +1 more source

The Multiple Roles of Lactate in the Skeletal Muscle [PDF]

Bartoloni, Bianca, Gamberi, Tania, Mannelli, Michele   +2 more
core  

Histone Lactylation-Mediated Metabolic Remodeling in Vascular Smooth Muscle Cells Aggravates Aortic Aneurysm and Dissection by Promoting Lactate Accumulation. [PDF]

Circulation
Liu L, Zhang J, Dong Z, Cui Y, Zou X, Lai H, Gu J, Weng X, Jin X, Qiu T, Pei Z, Hong W, Huang Y, Luo W, Pan L, Sun X, Zhang B, Shalamu A, Sun A, Ge J.   +19 more
europepmc   +1 more source

Histone lactylation-mediated up-regulation of IGF2BP2 enhances ferroptosis resistance via Nrf2 in colorectal cancer. [PDF]

Clin Transl Med
Zhu JF, Guo DP, Lv HN, Liang ZY, Song J, Zeng W.   +5 more
europepmc   +1 more source

Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome. [PDF]

Signal Transduct Target Ther
Yu C, Liu T, Wang Y, Guo X, Chen Y, Zhao Y, Liu X, Huang W, Zhao S, Mo J, Hu H, Lv P, Wang X, Yang Z, Pan J, Ding G, Sheng J, Liu X, Yang H, Huang HF.   +19 more
europepmc   +1 more source