Results 141 to 150 of about 4,116 (175)

Histone lactylation-mediated up-regulation of IGF2BP2 enhances ferroptosis resistance via Nrf2 in colorectal cancer. [PDF]

Clin Transl Med
Zhu JF, Guo DP, Lv HN, Liang ZY, Song J, Zeng W.   +5 more
europepmc   +1 more source

Histone Lactylation-Mediated Metabolic Remodeling in Vascular Smooth Muscle Cells Aggravates Aortic Aneurysm and Dissection by Promoting Lactate Accumulation. [PDF]

Circulation
Liu L, Zhang J, Dong Z, Cui Y, Zou X, Lai H, Gu J, Weng X, Jin X, Qiu T, Pei Z, Hong W, Huang Y, Luo W, Pan L, Sun X, Zhang B, Shalamu A, Sun A, Ge J.   +19 more
europepmc   +1 more source

<i>Helicobacter pylori</i> activates histone lactylation to promote gastric cancer progression and immune evasion through the HAS2/c-MYC/PD-L1 axis. [PDF]

Gut Microbes
Chen H, Wang Y, Wang Z, Su W, Shao Y, Zhang G, Wang Z, Ge Y, Zhou X.   +8 more
europepmc   +1 more source

Pyruvate kinase M2 -mediated histone lactylation alters three-dimensional genomic architecture in polycystic ovary syndrome. [PDF]

Signal Transduct Target Ther
Yu C, Liu T, Wang Y, Guo X, Chen Y, Zhao Y, Liu X, Huang W, Zhao S, Mo J, Hu H, Lv P, Wang X, Yang Z, Pan J, Ding G, Sheng J, Liu X, Yang H, Huang HF.   +19 more
europepmc   +1 more source

The Mechanisms and Research Advances of Histone Lactylation in Cancer

Advances in Clinical Medicine
openaire   +1 more source

Histone Lactylation-Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells. [PDF]

Adv Sci (Weinh)
Li J, Tang C, Zhang X, Xing R, Guo Q.
europepmc   +1 more source

AKR1B10 reprograms neutrophils by histone lactylation to foster immune evasion in KRAS^G12C mutation colorectal cancer liver metastasis. [PDF]

J Exp Clin Cancer Res
Li W, Yuan W, Du Z, Wang X, Wang D, Xing S, Shen T, Lu C, Chen J, Yu A, Jiang X, Zhang S, Zheng S, Feng X, Wang T, Zuo J, Chen J, Zhang C, Wang X, Zhang C.   +19 more
europepmc   +1 more source

Histone lactylation-driven feedback loop modulates cholesterol-linked immunosuppression in pancreatic cancer. [PDF]

Gut
Yang J, Yu X, Xiao M, Xu H, Tan Z, Lei Y, Guo Y, Wang W, Xu J, Shi S, Yu X.   +10 more
europepmc   +1 more source

Positive Feedback Loop of Histone Lactylation-Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance. [PDF]

Adv Sci (Weinh)
Huang XT, Chen J, Zhu EL, Ma MJ, Yu YY, Zhu YQ, Ye JY, Xie JZ, Zhao ZY, Yin XY.   +9 more
europepmc   +1 more source

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Augmentation of scleral glycolysis promotes myopia through histone lactylation

Cell Metabolism
Myopia is characterized of maladaptive increases in scleral fibroblast-to-myofibroblast transdifferentiation (FMT). Scleral hypoxia is a significant factor contributing to myopia, but how hypoxia induces myopia is poorly understood. Here, we showed that myopia in mice and guinea pigs was associated with hypoxia-induced increases in key glycolytic ...
Miaozhen Pan, Zhengbo Xue
exaly   +3 more sources