Results 21 to 30 of about 2,005,250 (367)
Epigenetic histone modifications in kidney disease and epigenetic memory. [PDF]
Clin Exp NephrolSasaki K, Masaki T.
europepmc +3 more sources
Histone modifications in neurodifferentiation of embryonic stem cells
Heliyon, 2022 Post-translational modifications of histone proteins regulate a long cascade of downstream cellular activities, including transcription and replication.
Min Huang +3 more
doaj +1 more source
Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues
Nature Biotechnology, 2021 In contrast to single-cell approaches for measuring gene expression and DNA accessibility, single-cell methods for analyzing histone modifications are limited by low sensitivity and throughput.
Marek Bartošovič +2 more
semanticscholar +1 more source
Histone Modifications in Alzheimer’s Disease
Genes, 2023 Since Late-onset Alzheimer’s disease (LOAD) derives from a combination of genetic variants and environmental factors, epigenetic modifications have been predicted to play a role in the etiopathology of LOAD.
D. A. Santana +2 more
semanticscholar +1 more source
Histone variants shape chromatin states in Arabidopsis
eLife, 2023 How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone ...
Bhagyshree Jamge +8 more
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Histones and histone modifications [PDF]
Current Biology, 2004 Histone variants, distinct patterns of posttranslational modifications of histones, and histone tail binding proteins all contribute to establishment of various ‘open’ or ‘closed’ chromatin domains that have specialized folding properties and biological functions. Some of these domains can be propagated through DNA replication and mitosis, guaranteeing
Peterson, Craig L, Laniel, Marc-André
openaire +2 more sources
Histone Modifications and Non-Coding RNAs: Mutual Epigenetic Regulation and Role in Pathogenesis
International Journal of Molecular Sciences, 2022 In the last few years, more and more scientists have suggested and confirmed that epigenetic regulators are tightly connected and form a comprehensive network of regulatory pathways and feedback loops.
I. Bure, M. Nemtsova, E. Kuznetsova
semanticscholar +1 more source
Histone onco-modifications [PDF]
Oncogene, 2011 Post-translational modification of histones provides an important regulatory platform for processes such as gene expression, DNA replication and repair, chromosome condensation and segregation and apoptosis. Disruption of these processes has been linked to the multistep process of carcinogenesis.
J, Füllgrabe, E, Kavanagh, B, Joseph
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Joint profiling of histone modifications and transcriptome in single cells from mouse brain
Nature Methods, 2021 Genome-wide profiling of histone modifications can reveal not only the location and activity state of regulatory elements, but also the regulatory mechanisms involved in cell-type-specific gene expression during development and disease pathology ...
Chenxu Zhu +5 more
semanticscholar +1 more source
Journal of Integrative Plant Biology, 2022 DNA methylation and histone modification are evolutionarily conserved epigenetic modifications that are crucial for the expression regulation of abiotic stress-responsive genes in plants.
Yutong Liu +3 more
semanticscholar +1 more source