Results 111 to 120 of about 34,607 (204)

Guidelines for Essential Trauma Care: Second Edition (2026)

open access: yesWorld Journal of Surgery, Volume 50, Issue 6, Page 1409-1450, June 2026.
Injury is a major cause of death and disability globally, with the highest burden in low‐ and middle‐income countries (LMICs). Strengthening the organization and planning for trauma care (care of the injured) can improve care and lower mortality. In 2004, the International Association for Trauma Surgery and Intensive Care (IATSIC) and the World Health ...
Charles Mock   +41 more
wiley   +1 more source

T‐Cell Biology in the Female Reproductive Tract: Relevance to HIV Infection

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT Worldwide, most HIV infections occur across a mucosal surface during sexual contact, with women accounting for nearly half of reported new HIV infections across the globe in 2024. Most new infections in women and girls are believed to involve transmission across mucosal surfaces of the lower reproductive tract, which includes the vagina and ...
Barbara L. Shacklett   +2 more
wiley   +1 more source

The Spatial Biology of HIV Transmission and Infection: Imaging the Female and Male Reproductive Tracts

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT HIV transmission through the female and male reproductive tracts is governed by spatially organized interactions between virions, epithelial barriers, and tissue‐resident immune cells. Imaging approaches have been central to defining these earliest events, progressing from classical histology and immunohistochemistry (IHC) to modern ...
Ann M. Carias   +3 more
wiley   +1 more source

Immune Modulation of HIV-1 Reservoir Size in Early-Treated Neonates. [PDF]

open access: yesJ Infect Dis, 2023
Hartana CA   +15 more
europepmc   +1 more source

The HIV Reservoir in the Female Reproductive Tract

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 6, June 2026.
ABSTRACT Antiretrovirals can prevent the spread of replicating HIV within the host and decrease the virus in plasma to levels undetectable in clinical assays, and in genital secretions to untransmissible levels. However, during effective treatment with antiretrovirals, infectious HIV persists lifelong because the virus integrates into the host's DNA ...
Sean M. Hughes, Lisa M. Frenkel
wiley   +1 more source

Prevalence of low‐level viremia and its association with virological failure among adolescents living with HIV in Eastern Cape, South Africa

open access: yesHIV Medicine, Volume 27, Issue 6, Page 1018-1030, June 2026.
Abstract Objectives Low‐level viremia (LLV) has been associated with an increased risk of virological failure among adults on antiretroviral therapy (ART). However, evidence on the clinical implications of LLV among adolescents living with HIV remains limited.
Zea Leon   +7 more
wiley   +1 more source

Phenotypic signatures of immune selection in HIV-1 reservoir cells. [PDF]

open access: yesNature, 2023
Sun W   +12 more
europepmc   +1 more source

Pediatric NIH Workshop: Session III—Specialties and Complexities of Juvenile NHP Models for HIV Prevention Research

open access: yesJournal of Medical Primatology, Volume 55, Issue 3, June 2026.
ABSTRACT Nonhuman primates (NHPs) have emerged as an indispensable model for studying HIV pathogenesis, vaccines, and therapies. The development of chimeric Simian/Human immunodeficiency viruses (SHIVs) has been constructed by inserting HIV‐1 Env into the SIV (usually SIVmac239) backbone, and these have proved essential for evaluating HIV neutralizing ...
A. J. Hessell   +2 more
wiley   +1 more source

Potent latency reversal by Tat RNA-containing nanoparticle enables multi-omic analysis of the HIV-1 reservoir. [PDF]

open access: yesNat Commun, 2023
Pardons M   +13 more
europepmc   +1 more source

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