Results 131 to 140 of about 34,792 (219)
HIV-1 reservoir evolution in infants infected with clade C from Mozambique. [PDF]
Koofhethile CK +16 more
europepmc +1 more source
ABSTRACT Sex hormones and reproductive transitions profoundly shape immune, metabolic, neuropsychological, and mucosal biology, as well as HIV persistence, across women's lives. Although women constitute the majority of people with HIV worldwide, hormonal and reproductive biology are still not sufficiently incorporated into HIV cure research. Cisgender
Elizabeth Hastie +18 more
wiley +1 more source
HIV-1 Reservoir Persistence and Decay: Implications for Cure Strategies. [PDF]
Kreider EF, Bar KJ.
europepmc +1 more source
Advancing Antiviral Design: Integrating Natural Products, Computation and Targeted Delivery
A stepwise translational framework linking natural‐product discovery, computational prioritisation, experimental validation, lead optimisation and targeted delivery is proposed to advance antiviral design. ABSTRACT The COVID‐19 pandemic highlighted the role of rapid viral mutation and global connectivity in accelerating viral emergence and spread ...
Adedayo Ayodeji Lanrewaju +3 more
wiley +1 more source
Progressive transformation of the HIV-1 reservoir cell profile over two decades of antiviral therapy. [PDF]
Lian X +23 more
europepmc +1 more source
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Changes in HIV-1 Reservoir Dynamics After Mpox Infection. [PDF]
Casado-Fernández G +14 more
europepmc +1 more source
TCR-mimic bispecific antibodies to target the HIV-1 reservoir. [PDF]
Sengupta S +24 more
europepmc +1 more source
Abstract Background The potent immunogenicity of mRNA vaccination raised concerns about its impact on HIV‐1 viral load (VL) and reservoir size in people with HIV, which could drive vaccine hesitancy. As part of a prospective clinical trial, we investigated whether SARS‐CoV‐2 mRNA vaccination induced changes in VL and reservoir size after a 1‐year three‐
Oscar Kieri +8 more
wiley +1 more source
Single-cell epigenetic, transcriptional, and protein profiling of latent and active HIV-1 reservoir revealed that IKZF3 promotes HIV-1 persistence. [PDF]
Wei Y +8 more
europepmc +1 more source

