Results 151 to 160 of about 33,958 (207)

On HIV-1 latency and viral reservoirs

, 2015
HIV-1 establishes a latent infection that is inaccessible to treatment in cellular and anatomical reservoirs. This thesis concerns several problematic issues of HIV-1 persistence, including ways to measure and monitor both the virus at low viral concentrations and the depletion of the reservoir.
openaire  

Transcriptomic HIV-1 reservoir profiling reveals a role for mitochondrial functionality in HIV-1 latency. [PDF]

PLoS Pathog
Man S, Jansen J, Kroeze S, Geijtenbeek TBH, Kootstra NA.   +4 more
europepmc   +1 more source

Autopsy Study Defines Composition and Dynamics of the HIV-1 Reservoir after Allogeneic Hematopoietic Stem Cell Transplantation with CCR5Δ32/Δ32 Donor Cells. [PDF]

Viruses, 2022
Huyveneers LEP, Bruns A, Stam A, Ellerbroek P, de Jong D, Nagy NA, Gumbs SBH, Tesselaar K, Bosman K, Salgado M, Hütter G, Brosens LAA, Kwon M, Diez Martin J, van der Meer JTM, de Kort TM, Sáez-Cirión A, Schulze Zur Wiesch J, Boelens JJ, Martinez-Picado J, Kuball JHE, Wensing AMJ, Nijhuis M, IciStem Consortium.   +23 more
europepmc   +1 more source

Evaluation of HIV-1 reservoir size and broadly neutralizing antibody susceptibility in acute antiretroviral therapy-treated individuals. [PDF]

AIDS, 2022
Moldt B, Günthard HF, Workowski KA, Little SJ, Eron JJ, Overton ET, Lehmann C, Rokx C, Kozal MJ, Gandhi RT, Braun DL, Parvangada A, Li J, Martin R, Selzer L, Cox S, Margot N, Liu H, Slamowitz D, Makadzange T, Collins SE, Geleziunas R, Callebaut C.   +22 more
europepmc   +1 more source

Footprints of innate immune activity during HIV-1 reservoir cell evolution in early-treated infection. [PDF]

J Exp Med
Sun W, Gao C, Gladkov GT, Roseto I, Carrere L, Parsons EM, Gasca-Capote C, Frater J, Fidler S, Yu XG, Lichterfeld M, RIVER Trial Study Group.   +11 more
europepmc   +1 more source

Differences in HIV-1 reservoir size, landscape characteristics, and decay dynamics in acute and chronic treated HIV-1 Clade C infection. [PDF]

Elife
Reddy K, Lee GQ, Reddy N, Chikowore TJB, Baisley K, Dong KL, Walker BD, Yu XG, Lichterfeld M, Ndung'u T.   +9 more
europepmc   +1 more source

Profound reduction of HIV-1 reservoir cells over 3 decades of antiretroviral therapy started in early infancy. [PDF]

JCI Insight
Vela LC, Carrere L, Naasz C, Kalavacherla S, Tan TS, de Armas L, Gao C, Yu XG, Pahwa SG, Luzuriaga K, Lichterfeld M.   +10 more
europepmc   +1 more source

Proliferation of HIV-1 reservoir cells: The delusion of infinite growth. [PDF]

J Exp Med
Lancien M, Lichterfeld M.
europepmc   +1 more source

Immune targeting of HIV-1 reservoir cells: a path to elimination strategies and cure. [PDF]

Nat Rev Microbiol
Armani-Tourret M, Bone B, Tan TS, Sun W, Bellefroid M, Struyve T, Louella M, Yu XG, Lichterfeld M.   +8 more
europepmc   +1 more source

The HIV-1 reservoir landscape in persistent elite controllers and transient elite controllers. [PDF]

J Clin Invest
Gasca-Capote C, Lian X, Gao C, Roseto IC, Jiménez-León MR, Gladkov G, Camacho-Sojo MI, Pérez-Gómez A, Gallego I, Lopez-Cortes LE, Bachiller S, Vitalle J, Rafii-El-Idrissi Benhnia M, Ostos FJ, Collado-Romacho AR, Santos J, Palacios R, Gomez-Ayerbe C, Muñoz-Medina L, Ruiz-Sancho A, Frias M, Rivero-Juarez A, Roca-Oporto C, Hidalgo-Tenorio C, Rull A, Olalla J, Lopez-Ruz MA, Vidal F, Viladés C, Mastrangelo A, Cavassini M, Espinosa N, Perreau M, Peraire J, Rivero A, López-Cortes LF, Lichterfeld M, Yu XG, Ruiz-Mateos E.   +38 more
europepmc   +1 more source