Results 161 to 170 of about 34,607 (204)
Measuring the HIV-1 reservoir [PDF]
Nature Reviews Microbiology, 2019 The description of a method to measure the HIV-1 reservoir that quantifies intact and defective proviruses.
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HIV-1 subtypes and latent reservoirs
Current Opinion in HIV and AIDS, 2023Purpose of review We explore the current status of research on HIV-1 subtype-specific variations and their impact on HIV-1 latency. We also briefly address the controversy surrounding the decision-making process governing the ON/OFF states of HIV-1 transcription, specifically focusing on the regulatory elements, the long ...
Udaykumar, Ranga +2 more
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Seeding the HIV-1 reservoir [PDF]
Nature Reviews Microbiology, 2014 Claudio Nunes-Alves
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Current Opinion in Infectious Diseases, 1999
Combination therapy for HIV-1 infection can reduce viremia to undetectable levels, suggesting that prolonged treatment might eradicate the infection. However, one potential mechanism for viral persistence involves the establishment of a state of latent infection.
J, Blankson, D, Persaud, R F, Siliciano
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Combination therapy for HIV-1 infection can reduce viremia to undetectable levels, suggesting that prolonged treatment might eradicate the infection. However, one potential mechanism for viral persistence involves the establishment of a state of latent infection.
J, Blankson, D, Persaud, R F, Siliciano
openaire +2 more sources
The prostate as a reservoir for HIV-1
AIDS, 2004As the prostate can harbor bacterial and fungal pathogens, it was investigated as a reservoir for HIV. Nine men chronically infected with HIV participated in a crossover trial in which weekly semen samples were collected with and without previous prostate massage (PM).
Davey M, Smith +5 more
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Immune control of HIV-1 reservoirs
Current Opinion in HIV and AIDS, 2013To discuss the recent major advances in the understanding of how host immune defenses contribute to HIV reservoir control.Immune control of HIV-1 reservoirs is a two-step process: viral replication activation from latent reservoirs followed by elimination of virus-expressing cells by the host.
Brigitte, Autran +2 more
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Markers of the HIV-1 reservoir
Current Opinion in HIV and AIDS, 2018The HIV-1 reservoir is composed of infected cells poised to replicate and spread the virus upon treatment interruption. It constitutes the main obstacle toward an HIV-1 cure. Whether marker(s) may allow the detection of cells that form the reservoir is an outstanding question.
Timothée, Bruel, Olivier, Schwartz
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Clinics in Laboratory Medicine, 2002
In most infected individuals, HIV-1 replicates high levels throughout the duration of infection, including the clinically quiescent phase of disease. The level of this active viral replication correlates directly with disease progression and survival.
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In most infected individuals, HIV-1 replicates high levels throughout the duration of infection, including the clinically quiescent phase of disease. The level of this active viral replication correlates directly with disease progression and survival.
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Current Infectious Disease Reports, 1999
The success of antiretroviral therapy for HIV-1 infection has generated interest in mechanisms by which the virus can persist in the body despite the presence of drugs that effectively inhibit key steps in the virus life cycle. There are several potential cellular and anatomic reservoirs for HIV-1.
openaire +2 more sources
The success of antiretroviral therapy for HIV-1 infection has generated interest in mechanisms by which the virus can persist in the body despite the presence of drugs that effectively inhibit key steps in the virus life cycle. There are several potential cellular and anatomic reservoirs for HIV-1.
openaire +2 more sources