Results 161 to 170 of about 33,958 (207)

Bispecific antibodies promote natural killer cell-mediated elimination of HIV-1 reservoir cells. [PDF]

Nat Immunol
Board NL, Yuan Z, Wu F, Moskovljevic M, Ravi M, Sengupta S, Mun SS, Simonetti FR, Lai J, Tebas P, Lynn K, Hoh R, Deeks SG, Siliciano JD, Montaner LJ, Siliciano RF.   +15 more
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Long-term effects on immunological, inflammatory markers, and HIV-1 reservoir after switching to a two-drug versus maintaining a three-drug regimen based on integrase inhibitors. [PDF]

Front Immunol
Saborido-Alconchel A, Serna-Gallego A, Trujillo-Rodriguez M, Muñoz-Muela E, Álvarez-Ríos AI, Lozano C, Llaves-Flores S, Espinosa N, Roca-Oporto C, Herrero M, Sotomayor C, Gutierrez-Valencia A, Lopez-Cortes LF.   +12 more
europepmc   +1 more source

HIV-1 reservoir size after neonatal antiretroviral therapy and the potential to evaluate antiretroviral-therapy-free remission (IMPAACT P1115): a phase 1/2 proof-of-concept study. [PDF]

Lancet HIV
Persaud D, Bryson Y, Nelson BS, Tierney C, Cotton MF, Coletti A, Jao J, Spector SA, Mirochnick M, Capparelli EV, Costello D, Szewczyk J, Nicodimus N, Stranix-Chibanda L, Kekitiinwa AR, Korutaro V, Reding C, Carrington MN, Majji S, Yin DE, Jean-Philippe P, Chadwick EG.   +21 more
europepmc   +1 more source

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HIV-1 subtypes and latent reservoirs

Current Opinion in HIV and AIDS, 2023
Purpose of review We explore the current status of research on HIV-1 subtype-specific variations and their impact on HIV-1 latency. We also briefly address the controversy surrounding the decision-making process governing the ON/OFF states of HIV-1 transcription, specifically focusing on the regulatory elements, the long ...
Udaykumar, Ranga, Arun, Panchapakesan, Chhavi, Saini   +2 more
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Latent reservoirs for HIV-1

Current Opinion in Infectious Diseases, 1999
Combination therapy for HIV-1 infection can reduce viremia to undetectable levels, suggesting that prolonged treatment might eradicate the infection. However, one potential mechanism for viral persistence involves the establishment of a state of latent infection.
J, Blankson, D, Persaud, R F, Siliciano
openaire   +2 more sources

Analyzing the unperturbed HIV-1 T cell reservoir

Trends in Immunology, 2023
The latent reservoir for HIV-1 prevents cure but is difficult to characterize due to the low frequency of latently infected cells and the absence of unique markers. Sun et al. used single cell analysis of T cell surface phenotypes to provide evidence for immune selection of reservoir cells.
Brianna, Lopez, Robert F, Siliciano
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Immune control of HIV-1 reservoirs

Current Opinion in HIV and AIDS, 2013
To discuss the recent major advances in the understanding of how host immune defenses contribute to HIV reservoir control.Immune control of HIV-1 reservoirs is a two-step process: viral replication activation from latent reservoirs followed by elimination of virus-expressing cells by the host.
Brigitte, Autran, Benjamin, Descours, Charline, Bacchus   +2 more
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HIV-1 reservoirs

Clinics in Laboratory Medicine, 2002
In most infected individuals, HIV-1 replicates high levels throughout the duration of infection, including the clinically quiescent phase of disease. The level of this active viral replication correlates directly with disease progression and survival.
openaire   +2 more sources