Results 31 to 40 of about 57,531 (234)
A Case of Statin-Associated Autoimmune Myopathy. [PDF]
, 2017 A 70-year-old previously independent man developed progressive proximal leg weakness resulting in a fall at home suffering traumatic brain injury. He was prescribed a statin medication two years prior, but this was discontinued on admission to the ...
Dokukin, Andrei N +6 more
core +3 more sources
, 2022 HMG-CoA reductase is an essential enzyme responsible for the biosynthesis of cholesterol. Hyperactivity of HMG-CoA reductase will increase cholesterol production, leading to the elevation of blood cholesterol levels.
Adliani, Nur +3 more
core +2 more sources
Pteridines, 2002 We investigated the effects of by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors, cerivastatin and fluvastatin, on the induction of nitric oxide (NO) production in vascular smooth muscle cells ( VSMC) stimulated by interleukin-1β (1L-1) or in ...
Hattori Yoshiyuki +4 more
doaj +1 more source
Effect of Concomitant 3-Hydroxy-3-Methyl-Glutaryl-CoA Reductase Inhibitor Therapy on Creatine Phosphokinase Levels and Mortality Among Patients Receiving Daptomycin: Retrospective Cohort Study. [PDF]
, 2014 IntroductionThe prescribing information for daptomycin recommends discontinuing statin therapy during receipt of daptomycin. The literature supporting this recommendation is sparse.
Lodise, Thomas +4 more
core +1 more source
Journal of Lipid Research, 1990 Lymphatic drainage leads to a significant stimulation of both the cholesterol 7 alpha-hydroxylase and HMG-CoA reductase activity in rats (Björkhem et al. 1978. Biochem. Biophys. Res. Commun. 85: (532-540).
JE Akerlund, I Björkhem
doaj +1 more source
PREDIKSI INTERAKSI SENYAWA METABOLIT SEKUNDER TANAMAN BELUNTAS (Pluchea indica) TERHADAP HMGCoA REDUCTASE SECARA IN SILICO [PDF]
, 2023 Background: Hyperlipidemia is a condition of abnormal lipid levels in the blood. Pluchea indica plants has not been widely used as a traditional herbal treatment to treat hyperlipidemia.
Agung, Muhammad Sofwan
core
Journal of Lipid Research, 1982 The subcellular localization of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase in rat intestine was reinvestigated. Highly enriched fractions of endoplasmic reticulum and mitochondria were prepared from mucosal cells.
F J Field +3 more
doaj +1 more source
Solid State Fermentation: An Effective Method for Lovastatin Production by Fungi over Submerged Fermentation [PDF]
, 2012 The Enzyme 3-hydroxy-3-methylglutaryl-CoA reductase (HMG CoA reductase) catalyses conversion of HMG CoA to mevalonate during cholesterol biosynthesis. Lovastatin is used as an anti-cholesterol drug which blocks HMG CoA reductase activity.
Praveen, V.K., Savitha, J.
core
Effects of Fibre-Enriched Diets on Tissue Lipid Profiles of MSG Obese Rats [PDF]
, 2012 In order to investigate the influence of some fibre-enriched diets on tissue lipids in an animal model of obesity induced by the administration of monosodium glutamate (MSG), obese rats were fed diets containing 30% of Acha, Cassava, Maize and Plantain
Ademuyiwa, Oladipo +3 more
core +1 more source
Advanced Science, EarlyView.After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin +6 more
wiley +1 more source