Results 91 to 100 of about 25,300,433 (384)

Nutritional and Behavioral Intervention for Long‐Term Childhood Acute Leukemia Survivors With Metabolic Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Metabolic syndrome (MetS) is a common complication in survivors of childhood acute lymphoblastic and myeloid leukemia (AL), and a major risk factor for premature cardiovascular disease, type‐2‐diabetes, and metabolic dysfunction‐associated steatotic liver disease (MASLD).
Visentin Sandrine, Béliard Sophie, Renard Cécile, Caussy Cyrielle, Hamidou Zeinab, Romano David, Gacem Mélanie, Petit Arnaud, Saultier Paul, Borentain Patrick, Michel Gérard   +10 more
wiley   +1 more source

Targeting the Nrf2-Heme Oxygenase-1 Axis after Intracerebral Hemorrhage. [PDF]

, 2017
BACKGROUND: Injury to cells adjacent to an intracerebral hemorrhage (ICH) is likely mediated at least in part by toxins released from the hematoma that initiate complex and interacting injury cascades.
Chen-Roetling, Jing, Regan, Raymond F.
core   +1 more source

Transforming Growth Factor-β Induces Transcription Factors MafK and Bach1 to Suppress Expression of the Heme Oxygenase-1 Gene [PDF]

, 2013
Transforming growth factor-β (TGF-β) has multiple functions in embryogenesis, adult homeostasis, tissue repair, and development of cancer. Here, we report that TGF-β suppresses the transcriptional activation of the heme oxygenase-1 (HO-1) gene, which is ...
Igarashi Kazuhiko, Itoh Ken, Kamoshida Atsushi, Kato Mitsuyasu, Koinuma Daizo, Motohashi Hozumi, Ogami Tomohiro, Okita Yukari, Suzuki Hiroyuki, Yamamoto Masayuki, 加藤 光保, 鈴木 裕之   +11 more
core   +1 more source

SYNTHESIS OF FERRITE NANOPARTICLES WITH PROTEIN MOLECULES IMMOBILLIZED ON THEIR SURFACES

ASEAN Journal on Science and Technology for Development, 2017
The ferrite (a Fe3O4 – gFe2O3 mixed solution) fine particles, ~8 nm in size were synthesized from an aqueous solution. Trypsin, a proteolytic enzyme or a protein, was immobilized onto the surfaces of those particles during the synthesis process.
Tran Hoang Hai, Le Hong Phuc, Doan Thi Kim Dung, Nguyen Thi Le Huyen, Bui Duc Long, Nguyen Tien Thang, Vu Van Do, Nguyen Thi Nhu Quynh, Masanori Abe   +8 more
doaj   +1 more source

Efficacy of a novel water soluble curcumin derivative versus Tadalafile in mediating erectile function [PDF]

Journal of Bioscience and Applied Research, 2015
The present study was conducted to assess the efficacy of a novel curcumin derivative (NCD) versus Tadalafile in erectile signaling. The study was conducted on 15 control male rats and 75 diabetic male rats divided into the following groups:, diabetic ...
SA.M. Zaahkouk, G.A Hesham, Yehia M. Hussein, H.M Atta, Fouad Hanan   +4 more
doaj   +1 more source

HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress

Aging, 2019
Heat stress negatively affects reproduction in cattle by disrupting the normal function of ovarian granulosa cells (GCs), ultimately leading to oxidative damage and cell death via apoptosis.
Yi-Ru Wang, Caixia Yang, N. Elsheikh, Chengmin Li, Fangxiao Yang, Genlin Wang, Lian Li   +6 more
semanticscholar   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga, Angela Lopez‐Cortes, Reem Al‐Saadi, Suzanne Tugnait, Kristina Dzhuma, Catriona Duncan, Gordan Vujanic, Tanzina Chowdhury, Claudia Allemani, Michel P. Coleman, Kathy Pritchard‐Jones, the Children's Cancer and Leukaemia Group (CCLG) Renal Tumour Special Interest Group, Hugh Bishop, Anthony McCarthy, Pamela Kearns, Helen Rees, Amos Burke, Meriel Jenney, Jane Pears, Hamish Wallace, Milind Ronghe, Tanzina Chowdhury, Susan Picton, Emma Ross, Lisa Howell, Bernadette Brennan, Gail Halliday, Richard Grundy, Shaun Wilson, Sucheta Vaidya, Daniel Yeomanson, Jessica Bate, Vesna Pavasovic, Jessica Bate, Sabine Irtan, Jesper Brok, Minou Oostveen, Kristina Dzhuma, Mark Weeks, Richard Williams, Mark Powis, Max Pachl, Bruce Okoye, Naima Smeulders, Gordan Vujanic, Oystein Olsen, Tom Watson, Susan Shelmerdine, Dan Saunders, Angela Lopez-Cortes, Taryn Treger, Tom Jackson, Suzanne Tugnait, Lisa Howell, Tanzina Chowdhury, Sam Behjati, Angela Polanco   +56 more
wiley   +1 more source

Heme oxygenase-1 derived carbon monoxide suppresses Aβ1-42 toxicity in astrocytes [PDF]

, 2017
Neurodegeneration in Alzheimer’s disease (AD) is extensively studied, and the involvement of astrocytes and other cell types in this process has been described. However, the responses of astrocytes themselves to amyloid peptides ((A; the widely accepted
DJ Selkoe, PD Coleman, L Conforti, C Culmsee, AC LeBlanc, DE Bredesen, C Culmsee, JA Hardy, J Hardy, R Lent, JJ Rodriguez-Arellano, JJ Rodriguez, A Verkhratsky, V Parpura, V Parpura, JA Hewett, GC Petzold, Y Otsu, M Talantova, PR Angelova, D Lim, D Lim, MC Tomasini, D Aguirre-Rueda, J Vina, GT Sutherland, JX Jiang, G Esposito, DH Cho, T Nakamura, TP Misko, N Hettiarachchi, MM Al-Owais, ML Dallas, C Taille, JL Scragg, BJ Murphy, PJ Lee, RT Kinobe, AY Abramov, L Canevari, P Narayan, J Jacobson, AY Abramov, AY Abramov, MH Tran, T Malinski, A Almeida, R Dringen, JP Bolanos, V Thorns, HJ Luth, Z Gu, T Nakamura, J Qu, T Nakamura, H Ischiropoulos, MP Kummer, K Srisook, HM Schipper, HM Schipper, W Song, HM Schipper, K Chen, N Imuta, NT Hettiarachchi, ML Dallas, IF Smith, ML Dallas   +68 more
core   +1 more source

Dysiarenone from Marine Sponge Dysidea arenaria Attenuates ROS and Inflammation via Inhibition of 5-LOX/NF-κB/MAPKs and Upregulation of Nrf-2/OH-1 in RAW 264.7 Macrophages

Journal of Inflammation Research, 2021
Tian-Yong Hu,1,* Hua Zhang,1,* Yan-Yan Chen,1 Wei-Hua Jiao,2 Jun-Ting Fan,3 Zhi-Qiang Liu,1 Hou-Wen Lin,2 Bao-Hui Cheng1 1Shenzhen Key Laboratory of ENT, Institute of ENT and Longgang ENT Hospital, Shenzhen, 518172, People’s Republic of China ...
Hu TY, Zhang H, Chen YY, Jiao WH, Fan JT, Liu ZQ, Lin HW, Cheng BH   +7 more
doaj  

Crosstalk Between Oxidative Stress and Endoplasmic Reticulum (ER) Stress in Endothelial Dysfunction and Aberrant Angiogenesis Associated With Diabetes: A Focus on the Protective Roles of Heme Oxygenase (HO)-1

Frontiers in Physiology, 2019
Type-2 diabetes prevalence is continuing to rise worldwide due to physical inactivity and obesity epidemic. Diabetes and fluctuations of blood sugar are related to multiple micro- and macrovascular complications, that are attributed to oxidative stress ...
Hatem Maamoun, T. Benameur, G. Pintus, Shankar Munusamy, A. Agouni   +4 more
semanticscholar   +1 more source