Results 41 to 50 of about 456,511 (292)

HO-1 expression control in the rat glomerulus

Biochemical and Biophysical Research Communications, 2015
The differential localization of HO-1 in renal cells under conditions of injury, and the demonstration that exaggerated HO-1 expression can have detrimental rather than beneficial effects, raises the question of whether HO-1 expression in these cells is subject to control.
Detsika, M.G., Duann, P., Lianos, E.A.
openaire   +3 more sources

Induction of heme oxygenase-1 attenuates lipopolysaccharide-induced cyclooxygenase-2 expression in mouse brain endothelial cells [PDF]

, 2010
Background Prostaglandin E2 (PGE2), an arachidonic acid metabolite converted by cyclooxygenase-2 (COX-2), plays important roles in the regulation of endothelial functions in response to bacterial infection.
Ruey-Horng Shih, Chuen-Mao Yang
core   +1 more source

Chinese Herbs and Repurposing Old Drugs as Therapeutic Agents in the Regulation of Oxidative Stress and Inflammation in Pulmonary Diseases

Journal of Inflammation Research, 2021
Chien-Chung Yang,1,2 Chuen-Mao Yang3– 5 1Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital at Tao-Yuan, Kwei-San, Tao-Yuan, 33302, Taiwan; 2School of Traditional Chinese Medicine, College of Medicine, Chang Gung University ...
Yang CC, Yang CM
doaj  

Scrophularia koraiensis Nakai Attenuates Allergic Airway Inflammation via Suppression of NF-κB and Enhancement of Nrf2/HO-1 Signaling

Antioxidants, 2020
Scrophularia koraiensis Nakai (Scrophulariaceae) is a medicinal herb that grows in Korea and which has been widely used to treat fever, edema, neuritis and laryngitis.
Tae-Yang Jung, A Yeong Lee, Jun-Ho Song, Min Young Lee, Je-Oh Lim, Se-Jin Lee, Je-Won Ko, Na-Rae Shin, Jong-Choon Kim, In-Sik Shin, Joong-Sun Kim   +10 more
doaj   +1 more source

HO-1 extends to stem cells

Blood, 2008
In this issue of Blood , Cao and colleagues show that HO-1 plays a key role in the maintenance of HSCs by limiting the stress-induced proliferation of progenitors and the exhaustion of HSC populations.
openaire   +4 more sources

Communication and Language Profiles of Children Treated for Posterior Fossa Brain Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cognitive and language deficits are frequently reported sequelae of posterior fossa brain tumors (PFBT). Typically, delayed onset impedes prompt assessment and early intervention. This has devastating implications for quality of life.
Zara Sved, Meghan Hesse, Jennie Cusiter, Annabel Webb, Kimberley Docking   +4 more
wiley   +1 more source

Astaxanthin protects against MPP+-induced oxidative stress in PC12 cells via the HO-1/NOX2 axis [PDF]

, 2012
BACKGROUND: Although the etiology of PD remains unclear, increasing evidence has shown that oxidative stress plays an important role in its pathogenesis and that of other neurodegenerative disorders.
Bixia Huang, Qinyong Ye, Xiaochun Chen, Xiaodong Zhang, Yuangui Zhu   +4 more
core   +1 more source

HO-1 in Control of a Self-Eating Kidney [PDF]

Journal of the American Society of Nephrology, 2010
Autophagy, from Greek meaning self-eating, refers to the degradation of macromolecules and organelles by the lysosomal machinery of cells and is a tightly regulated and normally occurring process that helps maintain a balance among synthesis, degradation, and recycling of cellular components.
Pinelopi P, Kapitsinou, Volker H, Haase
openaire   +2 more sources

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski, Michael C. Frühwald, Gudrun Fleischhack, Stephan Tippelt, Pablo Hernáiz‐Driever, Olaf Witt, Astrid Gnekow, Christof Kramm, Matthias Eyrich, Johannes E. A. Wolf, Hermann Müller, Carsten Friedrich, Uwe R. Kordes, Denise Obrecht‐Sturm, Petra Ketteler, Barbara von Zezschwitz, Pascal Johann, Dominik Sturm, Karoline Nemes, Stefan Schönberger, Till Milde, Brigitte Bison, Monika Warmuth‐Metz, Torsten Pietsch, Ulrich Schüller, Arend Koch, David Capper, Martin Hasselblatt, Christian Thomas, Christian Hagel, Stefan M. Pfister, Felix Sahm, David T. W. Jones, Martin U. Schuhmann, Jürgen Krauss, Pedram Emami, Ahmed El Damaty, Rolf D. Kortmann, Rudolf Schwarz, Jürgen Debus, Mechthild Krause, Fabian Pohl, Holger Ottensmeier, Lisa Bußenius, Katja Baust, Andreas Faldum, Cecile Ronckers, Desiree Grabow, Martin Benesch, Thomas Perwein, Karin Dieckmann, Irene Slavc, Johannes Gojo, Nicolas U. Gerber, André O. von Bueren, Katrin Scheinemann, Gabriele Calaminus, Beate Timmermann, Ulrich‐Wilhelm Thomale, Martin Mynarek   +59 more
wiley   +1 more source

Heme oxygenase 1 improves glucoses metabolism and kidney histological alterations in diabetic rats [PDF]

, 2013
One important concern in the treatment of diabetes is the maintenance of glycemic levels and the prevention of diabetic nephropathy. Inducible heme oxygenase 1 (HO-1) is a rate-limiting enzyme thought to have antioxidant and cytoprotective roles.
Albertoni, Guilherme A., Borges, Fernanda T., Convento, Marcia B., Fernandes, Gabryelle S., Pessoa, Edson A., Ptilovanciv, Ellen O. N., Reis, Luciana A., Schor, Nestor, Simoes, Manuel J., Teixeira, Luciana C.   +9 more
core   +1 more source