PHD finger proteins function in plant development and abiotic stress responses: an overview
The plant homeodomain (PHD) finger with a conserved Cys4-His-Cys3 motif is a common zinc-binding domain, which is widely present in all eukaryotic genomes.
Wenli Quan +6 more
doaj +1 more source
JUNGBRUNNEN1 confers drought tolerance downstream of the HD-Zip I Transcription factor AtHB13 [PDF]
Low water availability is the major environmental factor limiting growth and productivity of plants and crops and is therefore considered of high importance for agriculture affected by climate change.
Allu, Annapurna D. +6 more
core +1 more source
Intercellular Trafficking of Homeodomain Proteins
Homeotic proteins have pivotal roles during the development of both plant and animals. Many homeotic proteins exert control over cell fate in cells where their genes are not expressed, i.e., in a non-cell autonomous manner. Cell-to-cell communication, which delivers critical information for position-dependent specification of cell fate, is an essential
Seon-Won Kim +10 more
openaire +2 more sources
HIPK2 (homeodomain interacting protein kinase 2) [PDF]
Review on HIPK2 (homeodomain interacting protein kinase 2), with data on DNA, on the protein encoded, and where the gene is implicated.
Sombroek, D, Hofmann, TG
openaire +2 more sources
Homeobox genes in normal and abnormal vasculogenesis [PDF]
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M +3 more
core +1 more source
The homeodomain transcription factor Hoxa2 interacts with and promotes the proteasomal degradation of the E3 ubiquitin protein ligase RCHY1. [PDF]
Hox proteins are conserved homeodomain transcription factors known to be crucial regulators of animal development. As transcription factors, the functions and modes of action (co-factors, target genes) of Hox proteins have been very well studied in a ...
Isabelle Bergiers +4 more
doaj +1 more source
The use of information theory in evolutionary biology
Information is a key concept in evolutionary biology. Information is stored in biological organism's genomes, and used to generate the organism as well as to maintain and control it. Information is also "that which evolves". When a population adapts to a
Adami +79 more
core +1 more source
Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface. [PDF]
Orofacial clefting represents the most common craniofacial birth defect. Cleft lip with or without cleft palate (CL/P) is genetically distinct from cleft palate only (CPO).
Berkes +78 more
core +1 more source
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cytosolic sequestration of Prep1 influences early stages of T cell development.
ObjectivePrep1 and Pbx2 are the main homeodomain DNA-binding proteins of the TALE (three amino acid loop extension) family expressed in the thymus. We previously reported reduced Pbx2 expression and defective thymocyte maturation in Prep1 hypomorphic ...
Dmitry Penkov +3 more
doaj +1 more source

